Successful treatment of advanced squamous cell carcinoma arising from mature cystic teratoma of the ovary with homologous recombination deficiency: A case report
Abstract:BackgroundSquamous cell carcinoma arising from mature cystic teratoma of the ovary (MCT-SCC) has a poor prognosis at advanced stages. Although the relationship between the homologous recombination deficiency (HRD) status and platinum-based chemotherapy sensitivity or poly (ADP ribose) polymerase (PARP) inhibitor efficacy in epithelial ovarian cancer has been demonstrated in clinical trials, the significance of the HRD status in MCT-SCC remains unclear.Case presentationA 73-year-old woman with no remarkable pas… Show more
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