Successful treatment of actinic reticuloid induced by whole-body topical application of mechlorethamine

Volden, G; Es, Falk; Wisløff-Nilssen, J; Se, Stenvold; Moseng, Dagfinn; Kavli, G; Midelfart, K.

doi:10.2340/0001555561353354

Cited by 15 publications

(6 citation statements)

References 3 publications

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“…Topical corticosteroids are offered in a range of potencies, from low‐potency steroids including fluocinolone acetonide 11 . to high‐potency steroids, such as clobetasole propionate 12 . With the utilization of hydrocolloid 12 or occlusive dressings made of plastic wrap, topical corticosteroids' absorption has been further improved.…”

Section: Discussionmentioning

confidence: 99%

Pretibial myxedema in Grave's disease: A case report and treatment review of the literature

Nguyen,

Van Le

et al. 2024

Clinical Case Reports

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Key Clinical MessagePretibial myxedema is a rare skin lesion in Grave's disease, which required topical glucocorticoid administration in long‐term treatment. The patient's lesion has shrunk and become flatter than before treatment.AbstractWe present a case of biopsy‐verified pretibial myxedema in a 70‐year‐old male patient with diagnosed hyperthyroidism and no prior history of Graves' disease. Topical corticosteroid and antithyroid drug administration led to successful resolution of the skin lesions. This case emphasizes the importance of considering pretibial myxedema even in atypical presentations of Graves' disease and underscores the value of prompt treatment.

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Section: Discussionmentioning

confidence: 99%

Pretibial myxedema in Grave's disease: A case report and treatment review of the literature

Nguyen,

Van Le

et al. 2024

Clinical Case Reports

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“…The occlusive dressing group did not demonstrate therapeutic superiority 14 . Nevertheless, in the observational study, clobetasol propionate and hydrocolloid occlusive dressing once a week led to the complete remission of disease in 89% of patients in 2 weeks 15 . Flurandrenolone tape used in the treatment of lichen simplex chronicus was well‐known.…”

Section: Introductionmentioning

confidence: 94%

“…The latest systematic review of treatments for lichen simplex chronicus pointed out that there was a lack of high‐quality, evidence‐based treatments for lichen simplex chronicus 1 . In the latest review, one RCT and one observational study examined the use of occlusion as adjunctive therapy with topical steroids showed conflicting outcomes 1,14,15 . In the RCT, treatment with 0.3% diflucortolone valerate twice daily with and without plastic occlusion was investigated.…”

Section: Introductionmentioning

confidence: 99%

“…1 In the latest review, one RCT and one observational study examined the use of occlusion as adjunctive therapy with topical steroids showed conflicting outcomes. 1,14,15 In the RCT, treatment with 0.3% diflucortolone valerate twice daily with and without plastic occlusion was investigated. The occlusive dressing group did not demonstrate therapeutic superiority.…”

mentioning

confidence: 99%

“…14 Nevertheless, in the observational study, clobetasol propionate and hydrocolloid occlusive dressing once a week led to the complete remission of disease in 89% of patients in 2 weeks. 15 Flurandrenolone tape used in the treatment of lichen simplex chronicus was well-known. However, duration and application method were not well documented, and the quality of the study was difficult to assess.…”

mentioning

confidence: 99%

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Effectiveness of 0.1% mometasone furoate under hydrocolloid dressing versus 0.1% mometasone furoate in patients with lichen simplex chronicus

2023

Skin Health and Disease

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There was a lack of high‐quality, evidence‐based treatment for lichen simplex chronicus (LSC). Topical steroid under hydrocolloid dressing treatment was investigated mostly in observational studies without investigation of the cost‐effectiveness and the methodology of application also varied without standardisation. To investigate the cost‐effectiveness of topical steroid under hydrocolloid dressing in the treatment of moderate to severe lichen simplex chronicus (LSC). The study aimed to provide a clear methodology that was replicable. A single‐blinded randomized controlled trial was carried out to compare the efficacy of 0.1% mometasone furoate cream with or without hydrocolloid dressing in patients suffering from moderate to severe LSC. Physician Global Assessment (PGA) score, Eczema Area and Severity Index (EASI) individual components score were assessed by a Dermatologist through clinical photos at week 0, 2, and 4. Pruritis Numerical Rating Scale (PNRS) was rated. Forty adult patients were recruited. The group with hydrocolloid dressing showed superior treatment efficacy. 20 out of 20 patients benefited from the hydrocolloid dressing with topical steroid while only 6 out of 20 patients benefited from topical steroid alone at week 2 regarding PGA. Similar result was obtained at week 4. Extra HK$ 132 was needed for each patient in hydrocolloid with topical steroid group. The number needed to treat (NNT) was 1.43 (95% CI: 1.42–1.44) at week 2 and 1.42 (95% CI: 1.41–1.44) at week 4 regarding PGA score improvement of ≥2. NNT analysis supported the cost‐effectiveness of adjunctive hydrocolloid dressing usage as the first‐line treatment in patients with moderate to severe LSC. This study added evidence to LSC treatment with a detailed and reproducible methodology.

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Cutaneous Photosensitivity Diseases

Ibbotson

Dawe

2016

Rook's Textbook of Dermatology, Ninth Edition

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The photodermatoses are a diverse group of diseases, some of which, such as polymorphic light eruption, are very common and others, such as hydroa vacciniforme or xeroderma pigmentosum, are rare. It is essential not to miss the diagnosis of these conditions and referral to a specialist photodiagnostic centre is advised for many patients. Management depends on the diagnosis but includes prevention and disease suppression. Photoprotection is a mainstay approach for the photodermatoses but is often not sufficient for disease control. Desensitization using photo(chemo)therapy regimens may be feasible and systemic therapies are sometimes needed. Photosensitivity, particularly if chronic and severe, can be associated with significant psychological morbidity, which must be considered. Awareness of the possibility of vitamin D deficiency is also required.

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Successful treatment of actinic reticuloid induced by whole-body topical application of mechlorethamine

Cited by 15 publications

References 3 publications

Pretibial myxedema in Grave's disease: A case report and treatment review of the literature

Pretibial myxedema in Grave's disease: A case report and treatment review of the literature

Effectiveness of 0.1% mometasone furoate under hydrocolloid dressing versus 0.1% mometasone furoate in patients with lichen simplex chronicus

Cutaneous Photosensitivity Diseases

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