IntroductionMeningioma is a common benign idiopathic extra-axial tumor arising in the outer layer of the leptomeninges from arachnoid cap cells. 1 Primary or metastasis brain tumors typically lead to the development of focal neurological deficits, such as hemiparesis, sensory deficiency, and aphasia. However, the external compression of the frontal lobes by meningioma does not cause any symptoms other than gradual changes in personality and comprehension until they are substantially enlarged, leading to its recognized diagnosis as a "silent tumor". 2 Meningiomas, as the most commonly seen intracranial tumors, account for approximately 13%-26% of intracranial tumors. Most of them are slow-growing, and many are parenthetically defined. 3 While the etiology of meningioma is unclear, researchers believe that these tumors occur irregularly and may be associated with neurofibromatosis 2 (NF2), meningioangiomatosis (MA) and Gorlin syndrome as a family syndrome. 1,4 The clinical symptoms are typically based on the anatomical location. 5 We present a woman with depression and changes in personality, which displayed spaceoccupying lesions on further examination, indicating a giant frontal meningioma which we successfully removed.
Case PresentationA 24-year-old woman without a prior medical and psychological history was referred for inappropriate activity to a psychiatric clinic. She mainly had signs of depression, changes in personality, and was easily irritable, frustrated, and mentally stressed. With low memory and blurred vision, she had been forgetful as well. She had no history of head trauma, neurological focal deficit, or mental illness. She never consumed or smoked alcohol and did not use any illicit drugs.She was found to be time, place, and person-oriented on examination but had low attention and focus with poor judgments. Her score on the Mini-Mental State Examination score was 25/30. With a pulse rate of 70 beats/min, her blood pressure was 120/70 mm Hg. Fundoscopy did not show pink papillae, or any border or hemorrhage. Neurological investigations were all unremarkable, including cranial nerve and other systemic examinations. The results of her blood test were normal. A brain magnetic resonance imaging (MRI) was requested, and the results showed a well-defined significantly enhancing lesion in the left frontal region measuring 65 × 70 × 70 mm, with a fairly even edge, compression on the adjacent brain parenchyma with an associated significant