Successful topical treatment of focal epithelial hyperplasia (Heck's disease) with interferon-beta

Abstract

We report the successful topical treatment of focal epithelial hyperplasia (Heck's disease) with interferon-beta (Fiblaferon gel). Topical treatment with interferon-beta appears to be an effective, simple, non-invasive, cheap and low-risk alternative to other invasive or surgical therapeutic modalities.

Pediatric Dermatology Photoquiz: Multiple Papules on the Mucosal Surfaces of a 17‐Year‐Old Boy

“…Papillomas have been reported to regress without treatment in 12 to 18 months , but in patients seeking treatment, options include surgical removal, carbon dioxide laser surgery, cryosurgery, intralesional interferon, and topical podophyllum resin .…”

Viral diseases

“…672,673 Individuals with the HLA-DR allele HLA-DR4 (DRB1*0404) are at risk for the development of this disease. 465,[674][675][676][677] As for HPV infections at other sites, various treatments have been used including simple excision, electrocauterization, cryotherapy, and curettage. HPV-13 and 32 have been implicated in the etiology of this condition.…”

Hiperplasia epitelial focal (doença de Heck) em descendente de índios brasileiros: relato de caso

“…Assim, relacionando a presença dessa doença a certos grupos étnicos, podemos afirmar que é provável existir um co-fator genético (15) . Também sabemos da relação de subtipos do HPV 13 e/ou 32 com essa doença, o que pode ser demonstrado por estudos imuno-histoquímicos e, mais recentemente, utilizando hibridização in situ (9) .…”