Successful systemic thrombolytic therapy for massive pulmonary embolism in a patient with breast cancer, brain metastasis, and thrombocytopenia: A case report

Abstract

Key Clinical MessageA female with massive PTE and absolute contraindication for thrombolytic did not meet guidelines due to unavailability of catheter or surgical embolectomy and giving thrombolytic as a last resort to save a life. In such cases, physicians should consider to act outside of the guidelines to save a life.

Successfully thrombolysis using tenecteplase in a case of massive pulmonary embolism with multiple free-floating thromboses in the right atrium and right ventricle

“…In corresponding to a previous study, the present case has an absolute contraindication to thrombolytic therapy and high early mortality risk [ 10 ].…”

Rescue thrombolysis partial failure in massive PE complicated with in-transit thrombus

“…We were not sure of the safety and efficacy of repeat thrombolysis but it was the only available treatment option and we have experienced successful results from thrombolytic treatment in our previous cases 9,10. So, rescue thrombolysis was used only as a last resort for life saving and not as a standard step or current procedure.…”

Is thrombotic event a side effect of oral buprenorphine abuse? Two case reports

“…Intravenous alteplase was administrated according to approved dosage for massive PTE (100 mg infusion over a 2 hours’ period) . Approximately at the termination of the infusion, blood pressure returned to 100/70 mm Hg, with a heart rate of 95 beats per minute and a respiratory rate of 18 per minute with an oxygen saturation of 96% in ambient air.…”