“…4 This fact is underlined by the remarkable increase of reported infected coronary stents in the last decade: from the 24 coronary stent infection cases reported since 2003, 16 cases were with drug eluting stents (Tables 1 and 3). 43e 45,53,54,56,57,59,61,62,67e69,72,73 The drugs eluded by the stent were rapamycine, 43 sirolimus, 45,53,56,57,61,69 paclitaxel, 44,53,54,59,72 and everolimus. 68 The local inflammation, which leads to neointimal growth (caused by proliferation of smooth muscle cells), neointimal hyperplasia, and eventually restenosis, is inhibited by the immunosuppressive effects of the drugs.…”