Successful Summit of Two 8000 m Peaks After Recent High Altitude Pulmonary Edema

Dawadi, Suvash; Adhikari, Subarna

doi:10.1016/j.wem.2018.12.009

Cited by 5 publications

(1 citation statement)

References 14 publications

(30 reference statements)

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“…Everest [32] . Whereas in COVID-19, the coronavirus produces "alveolar-capillary cytolysis" and the intense inflammatory-immunological response destroys the lung tissue.…”

Section: Similarities and Differences With High Altitude Pulmonary Edmentioning

confidence: 99%

COVID-19: Multiple Diseases Simulating Extreme High-Altitude Exposure? Oxygen Transport Physiology and Scarce Need of Ventilators; Andean Condor’s-Eye-View

Zubieta-Calleja¹,

Zubieta-DeUrioste²,

Venkatesh³

et al. 2020

Preprint

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The critical hypoxia in COVID-19 patients during this pandemic, has taken away many lives all around the globe. The mechanism has been poorly understood and initially, word got around that it was a SARS (Severe Acute Respiratory Syndrome) pneumonia. The atypical images in lung computerized axial tomography (CAT) scans were alarming. This immediately alerted everyone including poor countries to purchase lacking sophisticated ventilator equipment. However, in some countries, even 88% of the patients on ventilators lost their lives. New observations and pathological findings are gradually clarifying the disease. What seems evident is that it is not only one disease but several, with different responses in different countries and different altitudes. The critical hypoxia and «gasping» present in some patients are not totally understood. It was mentioned that it could be like a High-Altitude Pulmonary Edema (HAPE). Hereby, as high-altitude medicine and hypoxia physiology specialists, we compare the pathophysiology with that of high-altitude exposure in order to understand the mechanisms involved. Some differences in lung radiological images along with transmission and viral attack mechanisms are discussed. The oxygen transport triad used at high-altitude can be applied on this pathology in order to propose even the use of erythropoietin (EPO) early in the treatment. The immune system is the most important long-term survival tool, so we suggest a short-term strategy: the use of special Earth open-circuit astronaut-resembling suits with effective outside air filtering re-breathing mechanisms in order to return to work and daily activities, without contamination risk. Thereby, the curve can be flattened without quarantine and the economy could recover.

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“…Everest [32] . Whereas in COVID-19, the coronavirus produces "alveolar-capillary cytolysis" and the intense inflammatory-immunological response destroys the lung tissue.…”

Section: Similarities and Differences With High Altitude Pulmonary Edmentioning

confidence: 99%

COVID-19: Multiple Diseases Simulating Extreme High-Altitude Exposure? Oxygen Transport Physiology and Scarce Need of Ventilators; Andean Condor’s-Eye-View

Zubieta-Calleja¹,

Zubieta-DeUrioste²,

Venkatesh³

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

Methamphetamine exacerbates pathophysiology of traumatic brain injury at high altitude. Neuroprotective effects of nanodelivery of a potent antioxidant compound H-290/51

Sharma

Lafuente

Feng

et al. 2021

Progress in Brain Research

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Military customized fabric hyperbaric chamber - design and safety aspects

Revaiah

Kotresh

Kandasubrmanian

2021

The Journal of The Textile Institute

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Successful Summit of Two 8000 m Peaks After Recent High Altitude Pulmonary Edema

Cited by 5 publications

References 14 publications

COVID-19: Multiple Diseases Simulating Extreme High-Altitude Exposure? Oxygen Transport Physiology and Scarce Need of Ventilators; Andean Condor’s-Eye-View

COVID-19: Multiple Diseases Simulating Extreme High-Altitude Exposure? Oxygen Transport Physiology and Scarce Need of Ventilators; Andean Condor’s-Eye-View

Methamphetamine exacerbates pathophysiology of traumatic brain injury at high altitude. Neuroprotective effects of nanodelivery of a potent antioxidant compound H-290/51

Military customized fabric hyperbaric chamber - design and safety aspects

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Successful Summit of Two 8000 m Peaks After Recent High Altitude Pulmonary Edema

Cited by 5 publications

References 14 publications

COVID-19: Multiple Diseases Simulating Extreme High-Altitude Exposure? Oxygen Transport Physiology and Scarce Need of Ventilators; Andean Condor&rsquo;s-Eye-View

COVID-19: Multiple Diseases Simulating Extreme High-Altitude Exposure? Oxygen Transport Physiology and Scarce Need of Ventilators; Andean Condor&rsquo;s-Eye-View

Methamphetamine exacerbates pathophysiology of traumatic brain injury at high altitude. Neuroprotective effects of nanodelivery of a potent antioxidant compound H-290/51

Military customized fabric hyperbaric chamber - design and safety aspects

Contact Info

Product

Resources

About

COVID-19: Multiple Diseases Simulating Extreme High-Altitude Exposure? Oxygen Transport Physiology and Scarce Need of Ventilators; Andean Condor’s-Eye-View

COVID-19: Multiple Diseases Simulating Extreme High-Altitude Exposure? Oxygen Transport Physiology and Scarce Need of Ventilators; Andean Condor’s-Eye-View