Successful stem cell collection for atypical teratoid rhabdoid tumor in an extremely low‐body weight child: A case report

Abstract

The use of peripheral blood hematopoietic stem cells for bone marrow reconstitution after myeloablative therapy is well established in children with malignant disorders. However, the peripheral blood hematopoietic stem cells collection in very low-body weight (≤10 kg) children remains a significant challenge because of technical and clinical issues. A male newborn affected by atypical teratoid rhabdoid tumor, diagnosed prenatally, received two cycles of

Successful peripheral blood stem cell harvesting for two pediatric cases of atypical teratoid/rhabdoid tumor with low bodyweight

“…Currently, there are no standardized guidelines for apheresis procedures in low-bodyweight children; therefore, various methods are used according to individual cases. [3][4][5] Children are susceptible to complications associated with apheresis such as hypotension and hypocalcemia. 6 Establishing vascular access is essential for safe and effective apheresis.…”