Successful resuscitation and neurological monitoring of a dog with out‐of‐hospital cardiopulmonary arrest due to pentobarbital overdose

Iannucci, Claudia; Hoehne, Sabrina N.; Murthy, Vishal D.; Dutil, Guillaume F; Maiolini, Arianna

doi:10.1111/vec.13283

Cited by 3 publications

(2 citation statements)

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“…32 There are also other publications that cited the WBDP's description of the minimum clinical criteria for BD/DNC determination as the reference standard and reinforced the message that BD/DNC is first and foremost a clinical assessment, and while nearly all of them refer to human patients, there is one case report on resuscitation of a dog after OHCA that mentioned the WBDP prescribes the need for observation prior to consideration of BD/DNC evaluation after HIBI. [99][100][101][102][103][104][105][106][107][108] New Publications Related to the Prerequisites for BD/DNC Determination Since publication of the WBDP, there have been a few publications on the prerequisites for BD/DNC evaluation including pharmacological and laboratory confounders and the requisite observation period. 4,32,[109][110][111][112][113] In a 2023 narrative review, Kanji et al expanded on the WBDP's guidance on pharmacological confounders to BD/DNC evaluation.…”

Section: Impact Of Wbdp Recommendations On the Minimum Criteria For B...mentioning

confidence: 99%

Section: Review Of the Wbdp And Updates Since Publicationmentioning

confidence: 99%

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An Update on Brain Death/Death by Neurologic Criteria since the World Brain Death Project

Lewis

2024

Semin Neurol

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The World Brain Death Project (WBDP) is a 2020 international consensus statement that provides historical background and recommendations on brain death/death by neurologic criteria (BD/DNC) determination. It addresses 13 topics including: (1) worldwide variance in BD/DNC, (2) the science of BD/DNC, (3) the concept of BD/DNC, (4) minimum clinical criteria for BD/DNC determination, (5) beyond minimum clinical BD/DNC determination, (6) pediatric and neonatal BD/DNC determination, (7) BD/DNC determination in patients on ECMO, (8) BD/DNC determination after treatment with targeted temperature management, (9) BD/DNC documentation, (10) qualification for and education on BD/DNC determination, (11) somatic support after BD/DNC for organ donation and other special circumstances, (12) religion and BD/DNC: managing requests to forego a BD/DNC evaluation or continue somatic support after BD/DNC, and (13) BD/DNC and the law. This review summarizes the WBDP content on each of these topics and highlights relevant work published from 2020 to 2023, including both the 192 citing publications and other publications on BD/DNC. Finally, it reviews questions for future research related to BD/DNC and emphasizes the need for national efforts to ensure the minimum standards for BD/DNC determination described in the WBDP are included in national BD/DNC guidelines and due consideration is given to the recommendations about social and legal aspects of BD/DNC determination.

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Section: Impact Of Wbdp Recommendations On the Minimum Criteria For B...mentioning

confidence: 99%

Section: Review Of the Wbdp And Updates Since Publicationmentioning

confidence: 99%

An Update on Brain Death/Death by Neurologic Criteria since the World Brain Death Project

Lewis

2024

Semin Neurol

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Letter to the Editor: Improving the effectiveness of CPR in all breeds of dogs

Rottenberg

2023

J Vet Emergen Crit Care

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Hoehne,

Iannucci,

Murthy

et al. 2023

J Vet Emergen Crit Care

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The described dog was successfully resuscitated by following recommendations outlined in the 2012 Reassessment Campaign on Veterinary Resuscitation (RECOVER) clinical guidelines. 2 These guidelines were developed after an extensive systematic literature review and evaluation, and their CPR algorithm groups CPR interventions into basic and advanced life support. 2,3 While basic life support interventions are recommended for all cardiopulmonary arrest patients, advanced life support drug and electrical therapies are informed by cardiac arrest rhythm diagnoses during patient reevaluations. 2 For animals with a documented nonshockable cardiac arrest rhythm, such as asystole in the described case, the administration of epinephrine 0.01 mg/kg IV every 4 minutes is currently recommended. 2 The patient outcome benefits of adhering to CPR guideline recommendations are well established in human resuscitative sciences. 4,5 Given recent similar evidence that demonstrates benefits of a RECOVER-based approach to CPR in dogs, the adherence to RECOVER guideline recommendations during clinical CPR efforts is standard practice at the reporting institution. 6 Veterinary CPR guidelines are not alone in recommending the administration of epinephrine to patients with nonshockable cardiac arrest rhythms. In 2019, the International Liaison Committee on Resuscitation conducted a systematic reassessment of epinephrine use during CPR. Review of the available literature culminated in the recommendation to administer epinephrine to patients with nonshockable cardiac arrest rhythms as soon as feasible during CPR; a recommendation that has since been maintained in guideline updates. 7,8 This recommendation is largely informed by 2 randomized controlled trials that found increased rates of return of spontaneous circulation (ROSC) and survival to hospital discharge in out-of-hospital cardiac arrest patients that were administered epinephrine versus saline placebo. 9,10 Although less strongly supported by the literature than epinephrine administration, atropine administration might be beneficial if increased parasympathetic tone or asphyxiation could have contributed to cardiopulmonary arrest. 2,11 Considering the case referral for uncontrolled and prolonged status epilepticus, a concern for intracranial hypertension, brain herniation, and increased parasympathetic tone was shared in the described patient.The authors agree with Mr. Rottenberg that high-quality basic life support measures represent the most important aspects of CPR, with-

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Successful resuscitation and neurological monitoring of a dog with out‐of‐hospital cardiopulmonary arrest due to pentobarbital overdose

Abstract: Objective: To describe the clinical signs, electroencephalographic (EEG) findings, treatment, and outcome in a dog after successful resuscitation from out-of-hospital cardiopulmonary arrest (OHCA) induced by pentobarbital intoxication.

Cited by 3 publications

References 28 publications

An Update on Brain Death/Death by Neurologic Criteria since the World Brain Death Project

An Update on Brain Death/Death by Neurologic Criteria since the World Brain Death Project

Letter to the Editor: Improving the effectiveness of CPR in all breeds of dogs

The authors respond

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