Successful public health action to reduce the incidence of symptomatic vitamin D deficiency

Moy, Robert; McGee, Eleanor; Debelle, Geoff; Mather, Ian H.; Shaw, Nicholas

doi:10.1136/archdischild-2012-302287

Cited by 48 publications

(59 citation statements)

References 7 publications

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“…Although there may be justified concerns over the low doses used in supplements, a recent study of universal supplementation reported considerable reduction in the incidence of symptomatic vitamin D deficiency in a child population. 21 As a result, NICE is considering the costeffectiveness of the Healthy Start vitamin programme becoming universal. 22 Vitamin D deficiency is an important public health issue.…”

Section: Discussionmentioning

confidence: 99%

Vitamin D assessment in primary care: changing patterns of testing

Zhao

Gardner

Taylor³

et al. 2015

London Journal of Primary Care

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. The number of vitamin D tests requested by primary care, and the associated cost, is rapidly increasing. . More cases of vitamin D deficiency were detected each year, but the odds of detecting deficiency decreased. . Repeat tests form a significant proportion of total requests, and should be performed after three to six months. . Seasonal variation in vitamin D levels should always be considered when requesting tests and interpreting results. Clinicians should consider risk factors for vitamin D deficiency to ensure targeted testing of patients. Why this matters to usThere is increasing awareness of the importance of vitamin D for maintaining musculoskeletal health by both the medical profession and the public. The number of requests for vitamin D testing from primary care is consequently increasing. Testing is expensive and can amount to a substantial financial burden, particularly if testing and retesting are performed inappropriately. There is a need to develop clear guidance for assessing vitamin D status in primary care. We believe our observations and recommendations will inform to improve the cost-effectiveness of vitamin D testing, its ability to influence management and thus make a real impact within primary care practice and patient care. Although this study was carried out in Liverpool, conclusions remain relevant to London given its greater black, Asian and minority ethnic population who are at increased risk of vitamin D deficiency.

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Section: Discussionmentioning

confidence: 99%

Vitamin D assessment in primary care: changing patterns of testing

Zhao

Gardner

Taylor³

et al. 2015

London Journal of Primary Care

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“…Nonetheless, vitamin D deficiency rickets is a treatable disease, and targeting preventative strategies at high risk populations, in whom the incidence rates are up to 200 times that of white children [20] may be appropriate. Indeed the incidence of symptomatic VDD in children aged less than 5 years more than halved following the introduction of universal free vitamin D supplements for all pregnant women and children under 5 years in Birmingham, where 75% of the population are from high risk ethnic backgrounds [108].…”

Section: Discussionmentioning

confidence: 99%

Vitamin D and skeletal health in infancy and childhood

et al. 2014

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During growth, severe vitamin D deficiency in childhood can result in symptomatic hypocalcaemia and rickets. Despite the suggestion from some studies of a secular increase in the incidence of rickets, this observation may be driven more by changes in population demographics than a true alteration to age, sex and ethnicity-specific incidence rates; indeed rickets remains uncommon overall and is rarely seen in fair-skinned children. Additionally, the impact of less severe vitamin D deficiency and insufficiency has received much interest in recent years, and in this review we consider the evidence relating vitamin D status to fracture risk and bone mineral density (BMD) in childhood and adolescence. We conclude that there is insufficient evidence to support the suggestion that low serum 25-hydroxyvitamin D [25(OH)D] increases childhood fracture risk. Overall, the relationship between 25(OH)D and BMD is inconsistent across studies and across skeletal sites within the same study; however there is evidence to suggest that vitamin D supplementation in children with the lowest levels of 25(OH)D might improve BMD. High quality randomised trials are now required to confirm this benefit.

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“…There are two studies looking at the impact of universal supplementation in groups at risk of vitamin D deficiency in the UK [28,29]. Moy et al [29] described that vitamin D supplementation with 400 IU/day led to a 59% fall in the incidence rate of symptomatic vitamin D deficiency and almost universal public awareness of vitamin D deficiency.…”

Section: Discussionmentioning

confidence: 99%

“…Moy et al [29] described that vitamin D supplementation with 400 IU/day led to a 59% fall in the incidence rate of symptomatic vitamin D deficiency and almost universal public awareness of vitamin D deficiency. Similarly, successful routine vitamin D supplementation was reported in refugees in Sydney, Australia [30].…”

Section: Discussionmentioning

confidence: 99%

Cross-sectional analysis of universal vitamin D supplementation in former East Germany during the first year of life

Siafarikas¹,

Deichl

Jahreis

et al. 2017

Journal of Pediatric Endocrinology and Metabolism

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Background: Universal vitamin D supplementation is controversial. Preventative examinations and public health initiatives in former East Germany that included vitamin D prophylaxis for children were regulated by official recommendations and guidelines. The aim of this study is to analyse the impact of a standardised nationwide guideline for universal supplementation with 400 International Units (IU) vitamin D3/day during the first year of life on clinical and biochemical parameters and the influence of surrounding factors. Methods: This is a cross-sectional analysis looking at data from a field study of 3481 term-born children during their first year of life that was conducted in 1989.

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Successful public health action to reduce the incidence of symptomatic vitamin D deficiency

Cited by 48 publications

References 7 publications

Vitamin D assessment in primary care: changing patterns of testing

Vitamin D assessment in primary care: changing patterns of testing

Vitamin D and skeletal health in infancy and childhood

Cross-sectional analysis of universal vitamin D supplementation in former East Germany during the first year of life

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