Successful pregnancy outcome after septum resection and use of amnion graft in patient with high transverse vaginal septum

Abstract

A 20-year-old woman recently married presented to the outpatient department of the hospital, with primary amenorrhea and difficulty in having coitus. Her height was 155 cm, breast development was normal for age, and other secondary sexual characters seemed normal. On local examination, external genitalia was normal looking, and there was no vaginal discharge. She had a blind vagina of 2 cm length. The ultrasound showed a normal-sized uterus and ovaries seemingly normal. Hormonal profile comprising serum follicle-stimulating hormone, luteinising hormone, prolactin and thyroid stimulating hormone were all within normal limits. Karyotyping was done, which showed a 46,XX pattern. The patient underwent vaginal surgery during which septum resection was done, and amnion grafting was performed to prevent stricture formation. The patient resumed successful coitus 3 months after surgery. There was no discomfort on coitus. She conceived 7 months later. Following this, the patient delivered a healthy baby boy through caesarean section at term.

Conception following successful repair of two previous failed attempts at repair of partial transverse vaginal septum diagnosed after marital union: A case report

“… 3 Some scholars have also described the use of a cut gut segment to bridge the vaginal gap, and skin grafts as well as amniotic membrane-coated vaginal mold have all been tried. 6 , 18 The aim is to encourage healing by epitheliosis rather than by fibrosis, which will lead to gynetresia. In our index patient, we improvised with the barrel of a 50-ml syringe, wrapped with cotton gauze and enveloped with a male condom and then wrapped with sufratulle gauze, which gave a very favorable outcome.…”

“…In a previous case report by Sohail et al on successful pregnancy following after transverse vaginal septum resection, the conception occurred 7 months following repair, and coitus was said to have resumed 3 months after surgery. 18 …”