Successful management of severe respiratory failure combining heliox with noninvasive high-frequency percussive ventilation

Stucki, Pascal; Scalfaro, Piétro; Halleux, Q de; Vermeulen, François; Rappaz, I.; Cotting, Jacques

doi:10.1097/00003246-200203000-00032

Cited by 12 publications

(8 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It stresses the potential benefits of heliox combined with high-frequency ventilation for improving severe respiratory failure, particularly in the setting of uncontrollable hypercapnia. [44] The use of heliox in combination with noninvasive positive pressure ventilation (NIPPV) in patients presenting with exacerbations of COPD will have to be added to the growing list of promising therapies for critically ill patients that could not be treated through other methods. [25] Helium is an inert gas with a very low density (0.18 g/L), which allows it to pass through narrowed passages with less turbulence than nitrogen or oxygen.…”

Section: Heliox and Mode Of Mechanical Ventilationmentioning

confidence: 99%

The use of heliox in critical care

Hashemian¹,

Fallahian²

2014

Int J Crit Illn Inj Sci

View full text Add to dashboard Cite

This paper reviews the medical use of helium oxygen mixture in obstructive airway disease in patients with croup, narrow endotracheal tubes (ETTs), respiratory distress syndrome, asthma, bronchiolitis, as well as patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) and acute lung injury. In addition, some other indications of heliox use and some innovative methods of ventilation applied in pediatrics and adults are presented through review of the literature of current decade. Yet, to recommend heliox use seems to require more research based on clinical practice and observation through vaster and more robust investigations.

show abstract

Section: Heliox and Mode Of Mechanical Ventilationmentioning

confidence: 99%

The use of heliox in critical care

Hashemian¹,

Fallahian²

2014

Int J Crit Illn Inj Sci

View full text Add to dashboard Cite

show abstract

“…Oral furosemide has not been shown to significantly improve status and should not be given 7. High‐frequency percussive ventilation (HFPV) is a pressure limited, time‐cycled, high‐frequency mode of ventilation that delivers subphysiologic tidal volumes at rapid rates and that can be used via an endotracheal tube, a nasal probe, or a face mask 8–10. In the endotracheal mode, in adults it has been shown to provide the same or improved oxygenation and ventilation at lower peak, mean, and end‐expiratory pressures when compared with conventional ventilation 11, 12.…”

Section: Introductionmentioning

confidence: 99%

Nasal high frequency percussive ventilation versus nasal continuous positive airway pressure in transient tachypnea of the newborn: A pilot randomized controlled trial (NCT00556738)

Roque

Bertrand

Tandonnet

et al. 2010

Pediatric Pulmonology

View full text Add to dashboard Cite

Objective To determine whether nasal high frequency percussive ventilation (NHFPV) would decrease duration of transient tachypnea of the newborn (TTN) compared to nasal continuous positive airway pressure (NCPAP) in newborn infants. Methods A prospective, unmasked, randomized, controlled clinical trial was conducted in 46 eligible newborn infants who were hospitalized for TTN in the University Hospital of Bordeaux (France) between 2007 and 2009. Infants born by cesarian section ≥37 GA, ≥2,000g with diagnosis of TTN and with a transcutaneous saturation <90% at 20 min after birth were eligible. Infants were randomized to either NHFPV or NCPAP. The primary endpoint was a reduction of the duration of TTN. Secondary endpoints were the duration of oxygen therapy and the minimal level required to obtain a saturation between 90% and 96% integrated into an index which included a time factor: [(FiO2—21)/time of O2 therapy]. Results In the NHFPV group the duration of TTN was half the time of NCPAP group (105 min ± 20 and 377 min ± 150, respectively; P < 0.0001). There was a significant decrease in duration of oxygen supplementation in the NHFPV group (6.3 min ± 3.3) compared to the NCPAP group (19.1 min ± 8.1; P < 0.001), and a significant decrease in level of oxygen supplementation [(FiO2—0.21)/time of O2 therapy] in the NHFPV group (0.29 min−1 ± 0.16) compared to the NCPAP group (0.46 min−1 ± 0.50; P < 0.001). There was no complication and NHFPV was as well tolerated as NCPAP. Conclusion NHFPV is well tolerated and more effective than NCPAP in treatment of TTN. NHFPV might be a novel and safe tool to manage TTN. Pediatr Pulmonol. 2011; 46:218–223. © 2011 Wiley‐Liss, Inc.

show abstract

“…When mixed with oxygen as heliox, the low density of helium reduces the resistance associated with gas delivery. This increased mobility has three effects: gas more readily reaches the alveoli, allowing greater diffusion; breathing effort is significantly reduced with use of a less-dense gas; and carbon dioxide (CO 2 ) is eliminated more rapidly [1-5]. …”

Section: Introductionmentioning

confidence: 99%

“…Gupta et al reported combined use of heliox and HFJV to enhance CO 2 elimination in a 5-month-old infant with acute respiratory failure, gas-trapping, hypercarbia, respiratory acidosis, and air leak syndrome [7]. Stucki et al reported successful use of heliox with high-frequency percussive ventilation in a 5-year-old boy with cystic fibrosis and severe acute respiratory failure [5]. Katz et al used an in vivo model of acute lung injury and found that high-frequency membrane-type oscillator ventilation with heliox improved oxygenation and CO 2 elimination.…”

Section: Introductionmentioning

confidence: 99%

Effects of heliox as carrier gas on ventilation and oxygenation in an animal model of piston-type HFOV: a crossover experimental study

2010

View full text Add to dashboard Cite

ObjectiveThis study aimed to compare gas exchange with heliox and oxygen-enriched air during piston-type high-frequency oscillatory ventilation (HFOV). We hypothesized that helium gas would improve both carbon dioxide elimination and arterial oxygenation during piston-type HFOV.MethodFive rabbits were prepared and ventilated by piston-type HFOV with carrier 50% helium/oxygen (heliox50) or 50% oxygen/nitrogen (nitrogen50) gas mixture in a crossover study. Changing the gas mixture from nitrogen50 to heliox50 and back was performed five times per animal with constant ventilation parameters. Arterial blood gas, vital function and respiratory test indices were recorded.ResultsCompared with nitrogen50, heliox50 did not change PaCO2 when stroke volume remained constant, but significantly reduced PaCO2 after alignment of amplitude pressure. No significant changes in PaO2 were seen despite significant decreases in mean airway pressure with heliox50 compared with nitrogen50.ConclusionThis study demonstrated that heliox enhances CO2 elimination and maintains oxygenation at the same amplitude but with lower airway pressure compared to air/O2 mix gas during piston-type HFOV.

show abstract

Successful management of severe respiratory failure combining heliox with noninvasive high-frequency percussive ventilation

Cited by 12 publications

References 9 publications

The use of heliox in critical care

The use of heliox in critical care

Nasal high frequency percussive ventilation versus nasal continuous positive airway pressure in transient tachypnea of the newborn: A pilot randomized controlled trial (NCT00556738)

Effects of heliox as carrier gas on ventilation and oxygenation in an animal model of piston-type HFOV: a crossover experimental study

Contact Info

Product

Resources

About