Successful management of recalcitrant perianal warts with two sessions of intralesional 5-fluorouracil

Bubna, Aditya Kumar

doi:10.4103/0253-7184.185499

Cited by 2 publications

(3 citation statements)

References 5 publications

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“…In the investigation of [11], for instance, the portion of 5-fu was 4mL of 50 mg/mL 5-fluorouracil. In the investigation of [14], the portion of 5-fu was 2ml. In the investigation of [9], the portion was 0.1ml/cm2 of 5-FU, 50mg/ml.In the current examination 5-fu has been attempted in a portion of 0.2 ml for moles up to 5 mm, 0.2 to 0.5 ml for moles up to 10 mm and bigger moles got up to 1 ml.…”

Section: Discussionmentioning

confidence: 99%

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Intralesional Injection of 5-Fluorouracil in Verruca Vulgaris: Immunohistochemical and Clinical Study

El-Rifae

Agina

Akl

et al. 2020

Benha Journal of Applied Sciences

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VV speak to a problematic remedial issue for the two patients and doctors. In this investigation, we planned to assess the clinical adequacy and wellbeing of intralesional 5-fu in the treatment of headstrong vv in grown-up patients. It included 60 patients. Subjects and techniques: The patients were isolated into 2 gathering, Group I: As a benchmark group of 10 solid volunteers were biopsied from typical non sun unco vered skin utilizing 4-6mm punch biopsies and Group II: 50 patients with vv exposed to: Group IIa: 15 vv were biopsied before infusion of 5-fu for histological and immunohistochemical examination.Group IIb: 15 vv were biopsied after infusion of 5 -fu after 3,4and 7days for histological and immunohistochemical assessment. Infusions were rehashed like clockwork, most extreme for six infusions. Results : caspase-3 was somewhat communicated in completely contemplated instances of typical skin. Caspase-3 was communicated in just 40% of vv which have been biopsied before 5-fu infusion however after infusion the exepression expanded to 86.7%. The previously mentioned findings may reveal insight into the counter apoptotic physiologic part of caspase-3 in typical skin. Caspase-3 over articulation ater 5-fu infusion proposes a likely function of 5-fu on enlistment of apoptosisConclusion: 5-fu is a promising compelling and safe methodology for the treatment of different vv with high freedom rate, gentle and transient unfriendly impacts.

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Section: Discussionmentioning

confidence: 99%

“…Nonetheless, inferable from helpless entrance effective 5-FU has not been exceptionally viable. Intralesional instillation of 5-FU, then again, takes into account restorative focuses to adequately arrive at the ailing site, consequently encouraging mole relapse [14].…”

Section: Discussionmentioning

confidence: 99%

Intralesional Injection of 5-Fluorouracil in Verruca Vulgaris: Immunohistochemical and Clinical Study

El-Rifae

Agina

Akl

et al. 2020

Benha Journal of Applied Sciences

View full text Add to dashboard Cite

show abstract

“…It interferes with DNA synthesis and inhibits RNA synthesis []. Topical application of 5‐FU has been used for the treatment of dermatological conditions for nearly half a century [,]. Topical application of 5‐FU is a safe, effective, and tolerable treatment for warts caused by HPV in children and adults [].…”

Section: Discussionmentioning

confidence: 99%

A case of papilloma associated with topical tacrolimus ointment for tongue ulcers

Masui

Hamada

Yura

2018

Oral Science International

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We report a case of tongue papilloma that developed after the topical administration of tacrolimus. A 68‐year‐old man was admitted to our hospital with pain in his mouth. The diagnosis was ulcerative stomatitis. Although corticosteroids were ineffective, marked improvements were noted with the use of tacrolimus ointment. During follow‐up observations, papillomas were observed on the tongue at the site of ointment application. The recurrence of papillary lesions was noted, but the lesions disappeared following the oral administration of a 5‐fluorouracil formulation after pancreatic cancer surgery. In this case, tacrolimus ointment may have been associated with the formation of papilloma on the tongue.

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Successful management of recalcitrant perianal warts with two sessions of intralesional 5-fluorouracil

Cited by 2 publications

References 5 publications

Intralesional Injection of 5-Fluorouracil in Verruca Vulgaris: Immunohistochemical and Clinical Study

Intralesional Injection of 5-Fluorouracil in Verruca Vulgaris: Immunohistochemical and Clinical Study

A case of papilloma associated with topical tacrolimus ointment for tongue ulcers

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