Successful lysis in massive pulmonary embolism with thrombus entrapped in PFO

Küçükseymen, Selçuk; Bayar, Nermin; Köklü, Erkan; Arslan, Şakir

doi:10.1016/j.ajem.2016.07.039

Cited by 3 publications

(1 citation statement)

References 7 publications

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“…Anticoagulation and thrombolysis therapy seem to be hazardous in patients with a large thrombus-in-transit within a PFO because of the high risk of either fragmentation or complete embolization. 11 However, Rose et al 12 reviewed many such cases during a 34-year period and showed that the mortality rate was lower after thrombolytic therapy than surgery. Our patient was hemodynamically stable, but she reported that her chest tightness and shortness of breath were worsening.…”

Section: Discussionmentioning

confidence: 99%

Large thrombus-in-transit within a patent foramen ovale in a patient with pulmonary embolism: a case report

Wang

et al. 2018

J Int Med Res

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ObjectiveA patent foramen ovale (PFO) is detected frequently by echocardiography. However, a thrombus trapped in a PFO is relatively rare. We herein describe a rare case of a 51-year-old patient with pulmonary embolism in which a large thrombus-in-transit through a PFO was found by echocardiography and disappeared after treatment.MethodsA 51-year-old woman presented with a 1-week history of chest tightness, unspecified chest pain, and shortness of breath. Echocardiography revealed a large thrombus trapped in a PFO with increased pulmonary artery pressure, which is a very rare and critical condition.ResultsThe patient was treated with thrombolysis and anticoagulation and discharged from the hospital with an uneventful recovery.ConclusionOur treatment of the present patient achieved a satisfactory result, but it may not be applicable to every patient. Echocardiography is a readily available and safe tool for demonstrating the size, location, and extent of a thrombus, and it plays an important role in the early diagnosis and treatment evaluation for patients with a thrombus trapped in a PFO with concurrent pulmonary embolism.

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Section: Discussionmentioning

confidence: 99%