Successful Long-term Immunotherapy for Human Seminal Plasma Anaphylaxis

Friedman, Stuart A.

doi:10.1001/jama.1984.03340440042025

Cited by 43 publications

(23 citation statements)

References 8 publications

(1 reference statement)

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“…Women identifying only pruritus as a systemic symptom were classified as localized responders. 2 Sampled pollutants of concern 3 Additional sampled pollutants of concern: Acid Gasses (Acetic, Formic, Hydrochloric, Nitric, Sulfuric) •twin**. Figure 11.…”

Section: Discussionmentioning

confidence: 99%

Investigation of Seminal Plasma Hypersensitivity Reactions (AIBS GWI 0046)

Bernstein¹

1999

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Section: Discussionmentioning

confidence: 99%

Investigation of Seminal Plasma Hypersensitivity Reactions (AIBS GWI 0046)

Bernstein¹

1999

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“…This was the first description of hypersensitivity to semen and over subsequent years a number of cases and series of cases have appeared in the medical literature [15] .…”

Section: Human Seminal Plasma Allergymentioning

confidence: 94%

Anaphylaxis and Human Seminal Plasma Allergy: A Review

Loka¹,

Gubbala²,

Srichurnam³

2015

jmscr

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“…26 Another option is the intravaginal route ; there have been reports of a few successful cases of intravaginal graded challenges using whole seminal plasma. 25 Regardless of the method of desensitization, pregnancies are possible for patients with SPA.…”

Section: Treatment/prognosismentioning

confidence: 99%

Seminal Plasma Allergy : A Literature Review

Nishihara

Shimizu²,

Ichihara

et al. 2015

J of Gen and Family Med

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Seminal plasma allergy (SPA) is an immunological reaction against human seminal plasma observed in women. SPA is not a well-known clinical syndrome, considering that there are few epidemiological studies on SPA, and it can often be overlooked or misdiagnosed as other medical conditions. Symptoms occur after sexual intercourse and manifest as systemic and/or localized symptoms. The pathophysiology of SPA is commonly assumed to be autoimmune reaction to seminal plasma with IgE antibodies ; however, it is still uncertain which specific antibodies cause SPA. In vivo skin tests, including prick and intradermal tests, are useful for diagnosing SPA. However, there has been no consensus on treatment of SPA, apart from symptomatic therapy, although several desensitization methods have been reported, using emergency kits for allergic reactions. The most common and most effective preventive measure for SPA is to use condoms during intercourse.

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Successful Long-term Immunotherapy for Human Seminal Plasma Anaphylaxis

Cited by 43 publications

References 8 publications

Investigation of Seminal Plasma Hypersensitivity Reactions (AIBS GWI 0046)

Investigation of Seminal Plasma Hypersensitivity Reactions (AIBS GWI 0046)

Anaphylaxis and Human Seminal Plasma Allergy: A Review

Seminal Plasma Allergy : A Literature Review

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