Successful living kidney donation from a patient with a Gitelman’s syndrome

Abstract

Living kidney donation from Gitelman’s syndrome (GS) patients remains very rare. Long-term renal prognosis of donor and recipient patients remains unknown. We report a 67-year-old man with GS, harbouring a mutation of the SLC12A3 gene, who donated his kidney for transplant. Five years post-transplantation, his clinical condition and biochemical parameters remained stable with close monitoring and follow-up. Patients with non-complicated GS can be considered eligible to donate their kidney for transplant.

Monogenic Kidney Diseases in Kidney Transplantation

“…The use of living donors with GKD has also been reported. Some patients with pauci-symptomatic genetic tubulopathy, such as Gitelman syndrome 152 , 153 , 154 , 155 , 156 might be suitable for organ donation with good midterm outcomes for both the donor and the recipient.…”