Successful Liver Transplantation in a Child With Langerhansʼ Cell Histiocytosis (Lch)

Liver transplantation in an adult with sclerosing cholangitis due to Langerhans cell histiocytosis

“…Lesions may be solitary or multi-focal and the clinical course is highly variable; those with multi-system involvement generally have a worse prognosis. Liver involvement occurs in 16-36% of multi-system LCH in the paediatric population and has been reported rarely in adults [1,2]. Liver disease in LCH has the clinical, histological and radiological hallmarks of sclerosing cholangitis and may progress rapidly [3].…”