“…She received inhaled steroid and beta-stimulants, and oral or intravenous theophylline, but was not intubated nor intensive care unit (ICU)-managed. She stayed for several days to 3 weeks for each admission from 6 months of age until 3 years and 11 months of age, when she was diagnosed with IgG2 deficiency and specific polysaccharide antibody deficiency, due to low serum IgG2 (57.4 mg/dL, with 58.5–292.1 mg/dL representing ±1.96 standard deviation (SD) range for healthy Japanese children 2–4 years old 7 ) and low anti-pneumococcal (PC) IgG2 (0.7 µg/mL, with 4.3 µg/mL representing an average level for healthy children 1–2 years old 8 ). Other IgG subclasses and IgG, IgA, and IgM, were within normal range (IgG1, 475.4 mg/dL; IgG3, 27.7 mg/dL; IgG4, 1.2 mg/dL; IgG, 526–562 mg/dL; IgA, 36 mg/dL; and IgM, 121 mg/dL).…”