Successful haploidentical BMT with post-transplant cyclophosphamide for refractory autoimmune pancytopenia after cord blood transplant in pediatric myelodysplastic syndrome
“…12 Similarly, Shima reported the combination of TBI with melphalan. 13 The usage of TBI as a part of haploSCT with a PTCY regimen is continued even in patients with Fanconi anemia 14,15 or in combination with busulfan. 16 Some reports in adults have investigated the possibility of a TBI-free conditioning regimen by replacing it with thiotepa and melphalan, but the trial was complicated by limited access to thiotepa and the group reversed to TBI.…”
Wawrzyniak-Dzierżek E, Gajek K, Ślęzak A, et al. Pediatric unmanipulated haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide and reduced intensity, TBI-free conditioning regimens in salvage transplantations.
“…12 Similarly, Shima reported the combination of TBI with melphalan. 13 The usage of TBI as a part of haploSCT with a PTCY regimen is continued even in patients with Fanconi anemia 14,15 or in combination with busulfan. 16 Some reports in adults have investigated the possibility of a TBI-free conditioning regimen by replacing it with thiotepa and melphalan, but the trial was complicated by limited access to thiotepa and the group reversed to TBI.…”
Wawrzyniak-Dzierżek E, Gajek K, Ślęzak A, et al. Pediatric unmanipulated haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide and reduced intensity, TBI-free conditioning regimens in salvage transplantations.
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