Successful Excision of a Left Ventricular Hamartoma

Parks, Floyd R.; Adams, Forrest H.; Longmire, William P.

doi:10.1161/01.cir.26.6.1316

Cited by 45 publications

(10 citation statements)

References 8 publications

(4 reference statements)

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“…Abnormalities of the ECG in cases of intramural fibroma include left ventricular hypertrophy and strain (Valledor et al, 1960;Parks et al, 1962;Hoen and Ellis, 1966), conduction defects (Jernstrom and Cremin, 1959;Edlund and Holmdahl, 1957), and cardiac arrhythmias (Jernstrom and Cremin, 1959). The appearance of pathological Q waves in leads over the site of the tumour has also been reported (gvejda and Tomasek, 1960;Osano et al, 1969).…”

Section: Discussionmentioning

confidence: 98%

“…Surgical removal of these tumours has been advocated (Geha et al, 1967) and this has been successful in infants (Parks et al, 1962;Geha et al, 1967;Bjork et al, 1967) and young children (Kay et al, 1968;Osano et al, 1969). One 17-month-old infant died shortly after complete removal of the tumour (Wilson et al, 1965).…”

Section: Discussionmentioning

confidence: 99%

“…Most of these intramural fibromas were found in infants and young children at either necropsy or thoracotomy, but over the past 15 years the diagnosis has been made before operation and in a few patients successful surgical removal has been accomplished (Parks, Adams, and Longmire, 1962;Geha et al, 1967;Bjork, Dahlgren, Rudhe, Zetterqvist, 1967;Kay et al, 1968;Osano et al, 1969).…”

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Intramural fibroma of the left ventricle

Hall

1971

Thorax

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A case of left ventricular fibroma in a symptomless 17-year-old girl is described. The tumour was extensive and after its removal inadequate left ventricular function resulted in death at operation. The role of surgical treatment is discussed.Primary tumours of the heart are rare (Prichard, 1951;Hudson, 1965;Heath, 1968) and particularly uncommon is the intramural ventricular fibroma; only 36 cases had been reported up to 1967 (Geha, Weidman, Soule, and McGoon, 1967). Most of these intramural fibromas were found in infants and young children at either necropsy or thoracotomy, but over the past 15 years the diagnosis has been made before operation and in a few patients successful surgical removal has been accomplished (Parks, Adams, and Longmire, 1962;Geha et al., 1967;Bjork, Dahlgren, Rudhe, Zetterqvist, 1967;Kay et al., 1968;Osano et al., 1969).Because of the rarity of these tumours Freeman, Geer, Randall, and Palfrey (1963) suggested that cases should be reported in order to increase knowledge of their natural history, diagnosis, and treatment. The case described here is that of a young girl with a large intramural fibroma of the left ventricle, diagnosed preoperatively, who died at operation. CASE REPORTThe patient, a 17-year-old girl, was referred to the Department of Cardiology, Royal Infirmary, Edinburgh, by her general practitioner who had detected a precordial systolic murmur at routine medical examination.She was asymptomatic and apart from common childhood illnesses her previous health had been excellent. On specific enquiry, however, she had noticed occasional 'missed beats' during the preceding few months.She was of average build with sinus arrhythmia and a systemic blood pressure of 115/60 mmHg. The jugular venous pulse was normal. There was no cardiomegaly and no thrill, but systolic pulsation was palpable at the upper left sternal edge. Heart sounds were normal with inspiratory splitting of the second heart sound and no accentuation of the pulmonary component. A short grade 2/6 mid-systolic murmur was heard in the pulmonary area but was not audible in the axillae or over the back. No ejection sound, diastolic murmur or other abnormal physical sign was detected.The electrocardiogram ( Fig. la and b) showed sinus arrhythmia with occasional ventricular extrasystoles and symmetrical inversion of the T waves in the high anterolateral leads. Her chest radiograph (Fig. 2) showed a localized bulge on the upper left heart border. Pulmonary arteries and pulmonary vascularity were normal. No calcification was detected at fluoroscopy. The full blood picture, blood urea, electrolytes, and plasma proteins were normal.At cardiac catheterization pressures and oxygen saturations on the right and left sides of the heart were normal. Cine-angiography, performed from the right and left ventricles, demonstrated a large mass encroaching on the outflow tract of both ventricles and displacing the interventricular septum to the right. The left atrium was also distorted and the left atrial appendage was not filled with c...

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Intramural fibroma of the left ventricle

Hall

1971

Thorax

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“…There is a tendency for these lesions to spontaneously regress during the first year of life 16. Cardiac fibroma is also primarily found in children17 , 18 and is a mass of fibrous and elastic tissue formed predominantly of collagen and fibroblasts 19. Fibroma is generally poorly vascularised and focally calcified, whereas hamartoma of mature cardiac muscle is non-calcific and may be highly vascularised with dilated venous channels 20.…”

Section: Differential Diagnosismentioning

confidence: 99%

Giant right atrial cystic hamartoma: a case report and literature review

Zhang

Yin²,

Yin

et al. 2009

Case Reports

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“…The earliest documentation of a cardiac fibroma dates back to 1559 [2], but the first well-documented case was reported by Luschka in 1855 [3]. Parks described the first successful removal of an intramural cardiac fibroma in 1962 [4]. Although benign, they are clinically important as they may present with symptoms of inflow and outflow obstruction, angina, arrhythmias, conduction disturbances and even death.…”

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confidence: 99%