Successful Endovascular Treatment of Carotid Aneurysms in a Patient with Vascular Ehlers-Danlos Syndrome

Chen, J. B.; Sun, Hong; Zhou, Liangxue; He, Min; Ding, Lei

doi:10.1055/s-0032-1322591

Cited by 4 publications

(3 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Vascular EDS patients have a high risk of mortality due to vascular fragility that often leads to hemorrhage (De Paepe and Malfait 2012). Intracranial aneurysms have been reported in both classical and non-classical forms of EDS, but relatively speaking it is patients with the vascular subtype of EDS who are at the highest risk for IBA formation (Chen et al 2013;Kato et al 2001;Kim et al 2016;Lummus et al 2014;Mirza et al 1979;Oderich et al 2005;Schievink et al 1990Schievink et al , 2002. Kim et al (2016) found intracranial aneurysms in 12 individuals, seven of whom had vascular EDS, from a chart review of 99 EDS patients (mean age 41.7 years) who underwent brain imaging.…”

Section: Ehlers-danlos Syndromementioning

confidence: 99%

A Review of the Genetics of Intracranial Berry Aneurysms and Implications for Genetic Counseling

Hitchcock

Gibson

2016

Journal of Genetic Counseling

View full text Add to dashboard Cite

Here we review the current understanding of the genetic architecture of intracranial berry aneurysms (IBA) to aid in the genetic counseling of patients at risk for this condition. The familial subtype of IBA, familial intracranial aneurysms (FIA), is associated with increased frequency of IBA, increased risk of rupture, and increased morbidity and mortality after rupture. Family history is the strongest predictor for the development of IBA. However, a genetic test is not yet available to assess risk within a family. Studies using linkage analysis, genome-wide association, and next-generation sequencing have found several candidate loci and genes associated with disease onset, but have not conclusively implicated a single gene. In addition to family history, a separate or concurrent diagnosis of autosomal dominant polycystic kidney disease is a strong genetic risk factor for IBA formation. We also discuss the relative risk for developing IBA in several Mendelian syndromes including vascular Ehlers-Danlos syndrome, Marfan syndrome, Neurofibromatosis Type I, and Loeys–Dietz syndrome.

show abstract

Section: Ehlers-danlos Syndromementioning

confidence: 99%

A Review of the Genetics of Intracranial Berry Aneurysms and Implications for Genetic Counseling

Hitchcock

Gibson

2016

Journal of Genetic Counseling

View full text Add to dashboard Cite

show abstract

“…Many of these aneurysms are pseudoaneurysms that arise as a result of trauma,2 9 21 iatrogenic injury,10 15 16 22 23 infection,7 19 radiation,8 11 22 25 or genetic abnormalities, such as fibromuscular dysplasia14 and Ehlers–Danlos syndrome 24. In our case, chronic otitis media is a possible etiology with progressive erosion into the left ICA, although we cannot rule out iatrogenic injury given a history of tympanoplasty.…”

Section: Discussionmentioning

confidence: 77%

Cervical–petrous internal carotid artery pseudoaneurysm presenting with otorrhagia treated with endovascular techniques

Leacy

Oermann

Skovrlj

et al. 2014

J NeuroIntervent Surg

View full text Add to dashboard Cite

Cervical-petrous internal carotid artery (CP-ICA) pseudoaneurysms are rare and have different etiologies, presentations, and treatment options. A middle-aged patient with a history of chronic otitis media presented with acute otorrhagia and was found to have a left-sided CP-ICA pseudoaneurysm. The patient was a poor surgical candidate with difficult arterial access. The pseudoaneurysm was treated with stand-alone coiling via a left brachial approach with persistent contrast filling seen only in the aneurysm neck at the end of the procedure. The patient re-presented 12 days later with repeat hemorrhage and rapid enlargement of the neck remnant, and was treated with a covered stent via a transcervical common carotid artery cut-down. A covered stent may provide a more definitive treatment for CP-ICA pseudoaneurysms compared with standalone coiling.

show abstract

“…In this review, there were 36 cases 6,7,10,16,27,28,30,36,38,39,41,48,51,[53][54][55][56]59,60,63,66,[70][71][72][73][74]78,[80][81][82]85,88 treated with interventional or surgical parent vessel occlusion only without bypass (Table 3).…”

Section: Treatment Strategies and Results From Literature Reviewmentioning

confidence: 99%

Petrous Internal Carotid Artery Aneurysm: A Systematic Review

et al. 2020

View full text Add to dashboard Cite

Object: Petrous internal carotid aneurysm (PA) concomitant with a mass lesion and cranial nerve palsy is relatively rare. In recent years, flow-diverter stent implantation is being widely used as an alternative treatment for PA. However, alternative treatments are not available for all patients for various reasons, including the tortuosity of the parent carotid artery, allergies to contrast material, or high cost. It is, therefore, important to compare the relative outcomes of different treatment methods. Here, we have accordingly reviewed the available literature on the treatments for PA. Methods: We searched PubMed, MEDLINE, and other databases, such as OvidSP using the terms "aneurysm ", "carotid artery", and "petrous " and identified 221 articles. We also performed a literature review and discussed and compared the etiologies, symptoms, treatment methods, and clinical outcomes in patients with PA. Results and Conclusions: The systematic review revealed that the onset of secondary aneurysms was generally manifested by bleeding (p<0.001), while the onset of primary aneurysms was manifested by cranial nerve deficits (p= 0.0014); the prognosis after treatment of 34 cranial nerve palsies in 25 cases was reported.

show abstract

Successful Endovascular Treatment of Carotid Aneurysms in a Patient with Vascular Ehlers-Danlos Syndrome

Abstract: This case report suggests that endovascular treatment of ICA aneurysms is feasible and can be achieved in patients with vascular EDS.

Cited by 4 publications

References 9 publications

A Review of the Genetics of Intracranial Berry Aneurysms and Implications for Genetic Counseling

A Review of the Genetics of Intracranial Berry Aneurysms and Implications for Genetic Counseling

Cervical–petrous internal carotid artery pseudoaneurysm presenting with otorrhagia treated with endovascular techniques

Petrous Internal Carotid Artery Aneurysm: A Systematic Review

Contact Info

Product

Resources

About