Successful Continuation of Pregnancy and Delivery in a Patient With Covid-19 Complicated by Multisystem Inflammatory Syndrome (Mis) and Cardiogenic Shock

Hou, Linle; Park, Byung Joon; Singh, Avneet; Vullaganti, Sirish; Lima, Brian; Stevens, Gerin R.; Jauhar, Rajiv; Grayver, Evelina

doi:10.1016/s0735-1097(21)03322-2

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A total of 221 patients with MIS-A were identified: 102 were from the CDC’s MIS-C surveillance system, of whom 55 were described in a recent publication; 20 were from voluntary reports to the CDC, of whom 9 were included in a recent publication; and 99 were from case reports published in the literature . Two clinician reviewers (P.P.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Clinical Characteristics of Multisystem Inflammatory Syndrome in Adults

et al. 2021

View full text Add to dashboard Cite

Key Points Question What are the clinical characteristics of multisystem inflammatory syndrome in adults (MIS-A)? Findings This systematic review of patients with MIS-A reported in the literature and to the US Centers for Disease Control and Prevention identified 221 patients worldwide. The syndrome presented approximately 4 weeks after acute COVID-19 with hyperinflammation and extrapulmonary multiorgan involvement that may be difficult to discern from acute biphasic COVID-19 and postacute sequelae of SARS-CoV-2 infection. Meaning These findings suggest that MIS-A occurs in the postacute COVID-19 period with a heterogeneous clinical presentation likely owing to a dysregulated immune response.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Authors were contacted for clarification if needed. In total, 449 relevant articles were identified, and 86 were selected for in-depth review; of these, 60 had data for patients with MIS-A Figure 1. summarizes the study selection process.…”

Section: Methodsmentioning

confidence: 99%

Clinical Characteristics of Multisystem Inflammatory Syndrome in Adults

et al. 2021

View full text Add to dashboard Cite

show abstract

A global systematic review and meta-analysis on the emerging evidence on risk factors, clinical characteristics, and prognosis of multisystem inflammatory syndrome in adults (MIS-A)

Qamar,

Afzal,

Dhillon

et al. 2023

Annals of Medicine &Amp; Surgery

View full text Add to dashboard Cite

Background: The multisystem inflammatory syndrome in adults (MIS-A) has emerged, similar to those in children associated with SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) [multisystem inflammatory syndrome in children (MIS-C)]. This review aimed to analyze the risk factors, clinical course, and prognosis of MIS-A. Methods: A comprehensive literature search was conducted using several databases for cases reporting MIS-A from 1 December 2019 till 9 September 2021. The case definitions used to identify potential cases were those recommended by the World Health Organization, Center for Disease Control, and individual country/physician classification. The meta-analysis was performed using Comprehensive Meta-Analysis (CMA) 2.2.027 and Review Manager (RevMan) 5.4.1, employing 95% confidence intervals (CI). Results: Seventy studies were assessed for full-text eligibility, out of which 37 were included. The mean age of the study population was 32.52±10.29 years. The most common symptoms were fever (89.8%, 95% CI: 77.7–95.7%) and diarrhea (49%, 95% CI: 35.4–62.7%). Ventricular tachycardia (57.1%, 95% CI: 43.1–70.1%) was the most common electro-cardiac abnormality. The most common inflammatory marker was elevated C-reactive protein (89.8%, 95% CI: 77.7–95.7%). Abnormal echocardiogram was the most common imaging test result (commonly, ventricular dysfunction and arrhythmias), while steroids were the most administered treatment. Severe cases had a higher need for vasopressor and inotropic support and antibiotic therapy compared to the non-severe cases. One death was reported due to cardiovascular failure. Conclusion: Our collated findings will help clinicians identify the typical presenting symptoms and optimal management of MIS-A. Further research is required to understand the long-term prognosis and the correlation between coronavirus disease 2019 (COVID-19) and MIS-A to understand its pathogenesis and clinical spectrum.

show abstract

Successful Continuation of Pregnancy and Delivery in a Patient With Covid-19 Complicated by Multisystem Inflammatory Syndrome (Mis) and Cardiogenic Shock

Cited by 2 publications

References 0 publications

Clinical Characteristics of Multisystem Inflammatory Syndrome in Adults

Clinical Characteristics of Multisystem Inflammatory Syndrome in Adults

A global systematic review and meta-analysis on the emerging evidence on risk factors, clinical characteristics, and prognosis of multisystem inflammatory syndrome in adults (MIS-A)

Contact Info

Product

Resources

About