Successful closure of a bronchopleural fistula by intrapleural administration of fibrin sealant: A case report with review of Literature

Abstract

Context:There are no established guidelines for the proper treatment of patients with bronchopleural fistulas (BPFs). Apart from attempts to close the fistula, emphasis of treatment and management is placed on preventive measures, early administration of antibiotics, drainage of the empyema and aggressive nutritional and rehabilitative support.Case Report:A 53-year-old male presented with nausea, vomiting, and dry cough with eventual respiratory failure. He was found to have an empyema of the left hemithorax which was managed with thoracostomy drainage and antibiotics. However, he had persistent air leak through the chest tube due to a BPF. Bronchoscopy failed to localize the involved segment. Application of fibrin glue through the chest tube succeeded in completely sealing the leak.Conclusion:To our knowledge, this is the first case report in which fibrin glue was successfully used intrapleurally to close a BPF related to an empyema.

Combined intrapleural and intrabronchial injection of fibrin glue for closing alveolar pleural fistula: a case report

“…Thus, we planned a personalized approach, not been reported before, as the combined intrapleural and intrabronchial injection of FG using fiber bronchoscopy. Kinoshita et al [5], and Shrestha et al [6] previously treated PAL by intrapleural injection of FG via a chest tube. In both cases, the FG was blindly injected within pleural cavity, while, in the present, the APF was sealed off under bronchoscopic view.…”