Successful Bridge Through Transplantation With Berlin Heart Ventricular Assist Device in a Child With Failing Fontan

Hoganson, David M.; Boston, Umar S.; Gazit, Avihu Z.; Canter, Charles E.; Eghtesady, Pirooz

doi:10.1016/j.athoracsur.2014.04.064

Cited by 41 publications

(28 citation statements)

References 8 publications

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“…Morales et al [20] reported a successful case of VAD implantation with the Heart Mate II in a 15-year-old Fontan patient with protein-losing enteropathy. Hoganson et al [21] reported successful bridge-toheart transplantation using a Berlin Heart VAD in a child. Niebler et al [22] presented a successful case of using a HeartWare VAD as a bridge to transplantation.…”

Section: Discussionmentioning

confidence: 98%

Partial cavopulmonary assist from the inferior vena cava to the pulmonary artery improves hemodynamics in failing Fontan circulation: a theoretical analysis

et al. 2015

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Cavopulmonary assist (CPA) for failing Fontan patients remains a challenging issue in the clinical setting. To evaluate the effectiveness of a partial CPA from the inferior vena cava (IVC) to the pulmonary artery (PA), we performed a theoretical analysis using a computational model of the Fontan circulation. Cardiac chambers and vascular systems were described as the time-varying elastance model and the modified three-element Windkessel model, respectively. A rotational pump described as a non-linear function was inserted between the IVC and the PA. When pulmonary vascular resistance index varied from 2.1 to 5.9 Wood units m(2), the partial CPA maintained cardiac index as efficiently as total CPA and markedly reduced the IVC pressure compared with total CPA. However, the partial CPA increased the superior vena cava pressure substantially. The modification from total to partial CPA is potentially an effective alternative in failing Fontan patients suffering from high IVC pressure.

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Section: Discussionmentioning

confidence: 98%

Partial cavopulmonary assist from the inferior vena cava to the pulmonary artery improves hemodynamics in failing Fontan circulation: a theoretical analysis

et al. 2015

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“…However, for patients with Fontan physiology, the experience with VAD use as BTT is limited. There are several reported cases of patients with Fontan physiology who underwent successful VAD implantation as BTT . A recent review of the EXCOR Investigational Device Exemption study database by Weinstein et al showed 42% mortality for 26 single ventricle patients supported with the Berlin VAD with 42% succesfully weaned to transplant and no patients weaned for recovery.…”

Section: Discussionmentioning

confidence: 99%

Berlin heart ventricular assist device as a long‐term bridge to transplantation in a Fontan patient with failing single ventricle

Halaweish

Ohye

R.A.S.

2015

Pediatric Transplantation

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The use of VADs as a BTT in children with heart failure has increased due to enhanced device design and reliability, leading to improved survival, functional capacity, and quality of life. However, the use of VADs in patients with Fontan physiology as a BTT is rare with few case reports. Here, we describe a case of implantation of the Berlin VAD as a BTT for 179 days, one of the longest reported periods of mechanical support, in a child with failing single ventricle.

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“…Several case reports of the use of commercially available implantable left ventricular assist devices have recently been published [41][42][43]. Biomechanical engineers are developing an axial flow impeller device for cavopulmonary assist, a mechanical circulation pulsation device using shape memory alloy fiber to augment inferior vena cava (IVC) to pulmonary artery flow, and there are animal studies of the use of the Jarvik device as a right-sided pump to augment flow from the IVC to the pulmonary artery [44][45][46].…”

Section: Heart Failurementioning

confidence: 98%

The Fontan operation

Hsu

2015

Current Opinion in Pediatrics

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Successful Bridge Through Transplantation With Berlin Heart Ventricular Assist Device in a Child With Failing Fontan

Cited by 41 publications

References 8 publications

Partial cavopulmonary assist from the inferior vena cava to the pulmonary artery improves hemodynamics in failing Fontan circulation: a theoretical analysis

Partial cavopulmonary assist from the inferior vena cava to the pulmonary artery improves hemodynamics in failing Fontan circulation: a theoretical analysis

Berlin heart ventricular assist device as a long‐term bridge to transplantation in a Fontan patient with failing single ventricle

The Fontan operation

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