“… 4 , 7 , 15 , 23 Moreover, there is a paucity of immunocompetent BRAF-mutated glioma murine models for the scientific community to elucidate these mechanisms of resistance. 24 Here, we present a novel immunocompetent RCAS-BRAF V600E murine model that resembles diffuse glioma PXA pLGG-like tumors. These tumors spontaneously transform from grade II to III until the mice decline.…”