Success Rates of Ankaferd Blood Stopper and Ferric Sulfate as Pulpotomy Agents in Primary Molars

Cantekin, Kenan; Gümüş, Hüsniye

doi:10.1155/2014/819605

Cited by 8 publications

(12 citation statements)

References 12 publications

(15 reference statements)

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“…This high percentage of success may be attributed to the anti-inflammatory, antibacterial potential of Ankaferd blood stopper . These results are in disagreement with a previous study which reported that: at the 3 and 6 month the clinical success rates of 100% was observed in ABS group and reduced to 90.9% at the 9 months (11) . However , this studies (10,11) and the current study revealed that time had no statistically significant effect on the overall cumulative clinical success.…”

Section: Discussioncontrasting

confidence: 99%

“…In the Formocrosol group, clinical success was 100% at 1and 3 months, 96.7% at 6 months and 90% at 9 months which revealed that time had no statistically significant effect on the overall cumulative clinical success.Regarding the radiographic evaluation, all radiographic signs of failure were absent at 3 months, 96.7% at 6 months and 86.7% at 9 month which revealed that time had no significant effect on the overall radiographic success (11) .…”

Section: Discussionmentioning

confidence: 89%

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Evaluation of Medicinal Plant Extract Versus Traditional Medicament Used for Vital Pulpotomy of Primary Molars

Sayed¹,

Fawzy

Hassan³

2019

ADJ-for Girls

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Purpose: To evaluate clinically, radiographically and histologically the postoperative success of Ankaferd Blood Stopper (ABS) and formocreosl (FC) in pulpotomy procedures for primary teeth. Materials and Method: 70 Primary molars found in 27 patients were selected according to inclusion criteria. In the first part of the study pulpotomy was accomplished in 22 patients having 60 teeth (30 each group) and depending on the type of radicular pulp medicament, the teeth were divided randomly and equally into 2 groups: Group I (FC) and Group II (ABS). Clinical follow up was done after 1, 3, 6 and 9 months.Periapical radiographs were taken at 3 , 6 and 9 months follow up visits. In the second part of the study 10 primary molars were found in 5 patients planned for extraction due to orthodontic purpose were treated by pulpotomy procedure. Teeth were divided into 2 groups (5 each group) and the teeth were extracted after 2 months for observation under light microscope. Results: No statistically significant difference between groups in the overall cumulative clinical or radiographic success at follow up periods. Histopathological examination revealed dentin bridge formation and continuous regular arrangement of odontoblastic layer at the pulp dentin junction along the root length in primary molars treated with ABS while FC specimens revealed Severe pulp hyperemia with thrombus formation at the entrance of pulp canal. Conclusion: Ankaferd blood stopper was found to be an acceptable alternative to formocresol pulpotomy agent with less inflammatory cell response and shorter application time.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 89%

Evaluation of Medicinal Plant Extract Versus Traditional Medicament Used for Vital Pulpotomy of Primary Molars

Sayed¹,

Fawzy

Hassan³

2019

ADJ-for Girls

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“…Study designs varied from split‐mouth type, matched contralateral molars in the same arch,to multiple teeth per child randomized to receive different treatments…”

Section: Discussionmentioning

confidence: 99%

Qualitative assessment of published studies on pulpotomy medicaments for primary molar teeth

Gopalakrishnan

Anthonappa

Ekambaram

et al. 2019

J of Invest & Clin Dent

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Pulpotomy has long been accepted as the treatment of choice for cariously-exposed primary teeth. Formocresol (FC), glutaraldehyde (GA), ferric sulfate (FS), calcium hydroxide (CH), electrosurgery (ES), laser, and mineral trioxide aggregate (MTA) are among the frequently-used pulpotomy medicaments. Although FC has been the gold standard for pulpotomies for over 80 years, following reports on the carcinogenicity of formaldehyde, 1 its use has been abandoned in several countries over the past decade. This stimulated extensive research to find an alternative medicament or technique that can achieve similar or greater success rates. GA, CH, FS, ES, laser, and MTA have all been evaluated through numerous clinical trials. 2-7 These data have been the basis for narrative 8,9 and systematic reviews. 10-12 While the true value of evidence-based systematic reviews and randomized clinical trials cannot be underestimated, they are limited by the quality of the studies included in those reviews.In 2006, Fuks and Papagiannoulis analyzed the quality of data from published clinical trials using a specifically modified version of standardized criteria. 13,14 They proposed a clear criterion-based grading system that was expected of a high-quality clinical trial designed to evaluate pulpotomies in primary teeth. A recent review applied the above criteria to evaluate the quality of evidence available to support the long-term efficacy of MTA for pulpotomies in primary teeth, and reported that there was no evidence that MTA AbstractThe aim of the present study was to perform a qualitative assessment of published clinical studies, using the Medline database between 2006 and 2016, on commonly used pulpotomy medicaments. Standardized criteria proposed by Fuks and Papagiannoulis in 2006 was used by three independent examiners who assessed a total of 64 studies and graded the papers as grades A (38-42), B1 (32-37), B2 (25-31), or C (<25) based on the score obtained. Dropout rates were calculated based on the initial sample and the final sample used for analysis. Only three papers were grade A, two of which were parts of the same clinical study with results presented at 24 and 42 months, respectively. Twelve papers were graded B1, 19 were graded B2, and 30 were graded C. The quality of evidence seemed greatest for formocresol (2 grade A, 21 grade B), followed by electro surgery (1 grade A study), calcium hydroxide (11 grade B studies), and ferric sulfate (11 grade B studies). The current qualitative assessment clearly highlights the inadequacies in the published studies, especially the study design and clinical and radiographic criteria, thus provides a basis for formulating specific guidelines for researchers embarking on conducting clinical trials on pulpotomy medicaments.

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“…Gupta et al 2015 [38] Pulpotomy procedures were performed by laser or electrosurgery. Cantekin et al 2014 [39] Authors compared the same pulpotomy dressing material. Trairatvorakul et al 2012 [40] Authors performed partial pulpotomy that is poorly reproducible and standardizable.…”

Section: Author Year Reason Of Exclusionmentioning

confidence: 99%

Different Pulp Dressing Materials for the Pulpotomy of Primary Teeth: A Systematic Review of the Literature

Bossù

Iaculli

Giorgio

et al. 2020

JCM

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Background: Pulpotomy of primary teeth provides favorable clinical results over time; however, to date, there is still not a consensus on an ideal pulp dressing material. Therefore, the aim of the present systematic review was to compare pulpotomy agents to establish a preferred material to use. Methods: After raising a PICO question, the PRISMA guideline was adopted to carry out an electronic search through the MEDLINE database to identify comparative studies on several pulp dressing agents, published up to October 2019. Results: The search resulted in 4274 records; after exclusion, a total of 41 papers were included in the present review. Mineral trioxide aggregate (MTA), Biodentine and ferric sulphate yielded good clinical results over time and might be safely used in the pulpotomies of primary molars. Among agents, MTA seemed to be the material of choice. On the contrary, calcium hydroxide showed the worst clinical performance. Although clinically successful, formocreosol should be replaced by other materials, due to its potential cytotoxicity and carcinogenicity. Conclusion: MTA seemed to be the gold standard material in the pulpotomy of primary teeth. Promising results were also provided by calcium silicate-based cements. Further randomized clinical trials (RCTs) with adequate sample sizes and long follow-ups are encouraged to support these outcomes. deciduous or young permanent teeth with immature roots affected by caries and without evidence of radicular pathology [7,8]. Nowadays, treatment options of VPT are represented by indirect pulp treatment (namely indirect pulp capping), direct pulp capping and pulpotomy [7]. Although clinically successful in primary molars, direct capping is mainly recommended in the VPT of permanent young teeth [9,10] and indirect capping seems to possess a relative effectiveness when compared to pulpotomy procedures [11]. The latter provides favorable clinical survival rates over time and allows the vitality of primary teeth until their natural exfoliation, avoiding pulpectomy procedures [2]. Pulpotomy consists of elimination of the bacterial infection by the removal of the pulp in the pulp chamber; then, the decontaminated tooth is filled with a medicament [11]. The most frequently used agents are mineral trioxide aggregate (MTA), Biodentine (BD), formocresol (FC), ferric sulphate (FS) and calcium hydroxide (CH). When compared, FC, FS and MTA seemed to provide significantly better clinical and radiographic results as pulpotomy agents than CH after two years of follow-up; moreover, MTA showed the best performance in respect to FC and FS over time [12]. Accordingly, Stringhini et al. [13] reported that MTA yielded superior clinical and radiographical results in comparison to FC. On the other hand, electrosurgery and FS showed similar success to FC, whereas CH did not show positive evidence as medicament in pulpotomies of primary teeth [13]. In the same way, Asgary et al. [14] further stressed that MTA demonstrated better long-term outcomes in pulpotomy of primary molars when com...

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Success Rates of Ankaferd Blood Stopper and Ferric Sulfate as Pulpotomy Agents in Primary Molars

Cited by 8 publications

References 12 publications

Evaluation of Medicinal Plant Extract Versus Traditional Medicament Used for Vital Pulpotomy of Primary Molars

Evaluation of Medicinal Plant Extract Versus Traditional Medicament Used for Vital Pulpotomy of Primary Molars

Qualitative assessment of published studies on pulpotomy medicaments for primary molar teeth

Different Pulp Dressing Materials for the Pulpotomy of Primary Teeth: A Systematic Review of the Literature

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