Subtyping of Panic Disorder by Symptom Profile

Briggs, Andrew C.; Stretch, David; Brandon, Sydney

doi:10.1192/bjp.163.2.201

Cited by 198 publications

(211 citation statements)

References 13 publications

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“…Fewer than half (n=12) were receiving a stable dose of psychotropic medications (benzodiazepines (n=6), antidepressants (n=4), beta-blockers (n=1), and other anxiolytics (n=1)). Based on DSM-IV panic symptoms reported during the initial structured diagnostic interview we classified 60% of the patients as belonging to a respiratory subgroup (Briggs et al, 1993). The majority of patients' (n=26) initial values of pCO 2 were in a hypocapnic range (pCO 2 <35 mmHg; Oakes, 1996).…”

Section: Recruitment and Patientsmentioning

confidence: 99%

Feedback of end-tidal pCO2 as a therapeutic approach for panic disorder

Meuret¹,

Wilhelm²,

Ritz³

et al. 2008

Journal of Psychiatric Research

142

124

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Background-Given growing evidence that respiratory dysregulation is a central feature of panic disorder (PD) interventions for panic that specifically target respiratory functions could prove clinically useful and scientifically informative. We tested the effectiveness of a new, brief, capnometry-assisted breathing therapy (BRT) on clinical and respiratory measures in PD.Methods-Thirty-seven participants with PD with or without agoraphobia were randomly assigned to BRT or to a delayed-treatment control group. Clinical status, respiration rate, and end-tidal pCO 2 were assessed at baseline, posttreatment, 2-month and 12-month follow-up. Respiratory measures were also assessed during homework exercises using a portable capnometer as a feedback device.Results-Significant improvements (in PD severity, agoraphobic avoidance, anxiety sensitivity, disability, and respiratory measures) were seen in treated but not untreated patients, with moderate to large effect sizes. Improvements were maintained at follow-up. Treatment compliance was high for session attendance and homework exercises; dropouts were few.Conclusions-The data provide preliminary evidence that raising end-tidal pCO 2 by means of capnometry feedback is therapeutically beneficial for panic patients. Replication and extension will be needed to verify this new treatment's efficacy and determine its mechanisms.

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Section: Recruitment and Patientsmentioning

confidence: 99%

Feedback of end-tidal pCO2 as a therapeutic approach for panic disorder

Meuret¹,

Wilhelm²,

Ritz³

et al. 2008

Journal of Psychiatric Research

142

124

View full text Add to dashboard Cite

show abstract

“…Patients were included in the respiratory subtype group if they had four or five of these respiratory symptoms during the PA; patients with three or less of these symptoms belonged to the non-respiratory subtype. The group with prominent respiratory symptoms suffered more spontaneous PAs, whereas patients in the non-respiratory subtype depicted more situational PAs 8 .…”

Section: Introductionmentioning

confidence: 99%

“…There is scientific evidence that the "respiratory symptoms" group is a distinct PD subtype 3,8 . Briggs et al 8 studied the descriptions of the most recent severe panic attack of 1108 PD patients and performed a principal component analysis of the symptoms.…”

Section: Introductionmentioning

confidence: 99%

“…Briggs et al 8 studied the descriptions of the most recent severe panic attack of 1108 PD patients and performed a principal component analysis of the symptoms. The symptoms of fear of dying, chest pain/discomfort, shortness of breath, paresthesias, and sensation of choking defined a distinct group and the absence of these symptoms defined another group.…”

Section: Introductionmentioning

confidence: 99%

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Are patients with panic disorder respiratory subtype more vulnerable to tobacco, alcohol or illicit drug use?

Freire

Nardi

2013

Rev. psiquiatr. clín.

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“…19 In the clinical setting, PD is a heterogeneous condition with diverse symptom patterns. Briggs et al 20 reported a homogeneous subgroup of PD patients in which shortness of breath and increased respiratory effort were the preponderant symptoms. This was called respiratory subtype panic disorder (RPD).…”

Section: Introductionmentioning

confidence: 99%

Panic disorder and exercise avoidance

Muotri

Bernik

2014

Rev. Bras. Psiquiatr.

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Objectives: 1) To identify whether patients with panic disorder in general and those with the respiratory subtype in particular actively avoid exercise; 2) to investigate physiological differences in cardiopulmonary function parameters in patients with panic disorder in general, patients with the respiratory subtype of panic disorder, and healthy controls upon exercise challenge. Methods: Patients with panic disorder were classified as having either the respiratory or the nonrespiratory subtype. Both groups were compared to controls in terms of exercise avoidance patterns and performance on cardiopulmonary exercise testing. Results: Patients with panic disorder exhibited higher exercise avoidance scores and worse performance on cardiopulmonary exercise testing as compared with controls. No differences were found between patients with the respiratory and non-respiratory subtypes. Conclusions: Exercise avoidance is present in panic disorder and is associated with poorer performance on cardiopulmonary exercise testing. These findings are not limited to patients with the respiratory subtype of the disorder.

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Subtyping of Panic Disorder by Symptom Profile

Cited by 198 publications

References 13 publications

Feedback of end-tidal pCO2 as a therapeutic approach for panic disorder

Feedback of end-tidal pCO2 as a therapeutic approach for panic disorder

Are patients with panic disorder respiratory subtype more vulnerable to tobacco, alcohol or illicit drug use?

Panic disorder and exercise avoidance

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