“…More recently, studies have demonstrated the identification and subsequent degeneration and death of various RGC subtypes in various injury and disease models, including axotomy, optic nerve crush, and glaucoma models (Birke et al, 2010;Cui et al, 2015;Daniel et al, 2018;Duan et al, 2015;El-Danaf and Huberman, 2015;Majander et al, 2017;Ou et al, 2016;Puyang et al, 2017;Yucel et al, 2003), suggesting subtype specific responses to injury. However, these few studies produced limited conclusions as to how various model systems affect RGCs and more specifically, which RGCs subtypes are highly affected in response to disease and injury.…”