Subtype B Was the Dominant Strain Among HIV Type 1 Infections Except for the Population of Men Who Have Sex with Men in Harbin City, China

Lei, Lei; Li, Wenjing; Liu, Ting; Li, Hang; Chang, Man-Li; Huang, Chao-Qun; Wang, Fuxiang; Wang, Binyou

doi:10.1089/aid.2013.0135

Cited by 9 publications

(10 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similarly with Choi's study [5], the present study found that the younger age of sexual debut with men was associated with larger size of social networks ( r = −0.15) and larger social networks were associated with the use of HIV prevention services. However, our findings differ with another report that suggests MSM sexual debut predicted more frequently change of sex partners and other risk behaviors [36].…”

Section: Discussionsupporting

confidence: 87%

HIV Prevention Services and Testing Utilization Behaviors among Men Who Have Sex with Men at Elevated Risk for HIV in Chongqing, China

Huang

Hu²,

Wu³

et al. 2014

BioMed Research International

View full text Add to dashboard Cite

Objective. To investigate barriers and correlates of the use of HIV prevention services and HIV testing behaviors among men who have sex with men in Chongqing. Methods. Three consecutive cross-sectional surveys provided demographic, sexual behavior, HIV/syphilis infection, HIV prevention service, and testing behavior data. Results. Of 1239 participants, 15.4% were infected with HIV, incidence was 12.3 per 100 persons/year (95% CI: 9.2–15.3), 38% of the participants reported ever having unprotected insertive anal sex, 40% ever received free condom/lubricants in the past year, and 27.7% ever obtained free sexually transmitted infection examination/treatment in the past year. Multivariable logistic regression revealed that lower levels of HIV/AIDS related stigmatizing/discriminatory attitudes, full-time jobs, and sex debut with men at a younger age were independently associated with use of free condom/lubricants. Large social networks, higher incomes, and sexual debut with men at a younger age were associated with use of any HIV prevention and HIV testing services. Lower levels of stigmatizing/discriminatory attitudes were also associated with HIV testing. Fearing needles and being unaware of the venues for testing were top barriers for testing service utilization. Conclusion. It is imperative to address HIV/AIDS related stigmatizing/discriminatory attitudes and other barriers while delivering intervention and testing services.

show abstract

Section: Discussionsupporting

confidence: 87%

HIV Prevention Services and Testing Utilization Behaviors among Men Who Have Sex with Men at Elevated Risk for HIV in Chongqing, China

Huang

Hu²,

Wu³

et al. 2014

BioMed Research International

View full text Add to dashboard Cite

show abstract

“… a These data came from the following references: Wang et al, ; Liu et al, ; Li et al, ; Shao et al, .…”

Section: Resultsmentioning

confidence: 99%

“…Third, because of the absence of CRF01_AE from all regions of the country, the epidemiologic characteristics of the CRF01_AE prevalence may not be intact nationwide. In addition, the sequences obtained successfully were disproportionate with the actual number of annual reported cases in Harbin during the a These data came from the following references: Wang et al, 2007;Liu et al, 2009;Li et al, 2012;Shao et al, 2013. b Present study included only one sequence from the blood sample collected in 2009. retrospective period. The results obtained from the present study mainly reflect the status of the HIV epidemic between 2011 and 2013.…”

Section: Discussionmentioning

confidence: 99%

Molecular epidemiology is becoming complex under the dynamic HIV prevalence: The perspective from Harbin, China

Lei

Song

Cao

et al. 2015

Journal of Medical Virology

Self Cite

View full text Add to dashboard Cite

Unlike most areas of China, HIV transmission via men who have sex with men (MSM) is increasing rapidly, and has become the main route of HIV transmission in Harbin city. The purpose of the current study was to elaborate the molecular epidemiologic characteristics of the new HIV epidemic. Eighty-one HIV-1 gag gene sequences (HXB2:806-1861) from local HIV infections were isolated; CRF01_AE predominated among HIV infections (71.6%), followed by subtype B (16.5%), CRF07_BC (6.2%), and unique recombinant strains (URFs; 6.2%). URFs were most often identified in the MSM population, which consisted of a recombination of CRF01_AE with subtype B or CRF07_BC. Six clusters were formed in this analysis; clusters I and II mainly circulated in southwest China. Clusters III and IV mainly circulated in southwest, southeast, and central China. Clusters V and VI mainly circulated in north and northeast China. Clusters III and IV may facilitate the transmission of the CRF01_AE strain from the southwest to the north and northeast regions of China. HIV subtypes are becoming diverse with the persistent epidemic in this geographic region. In brief, our results indicate that the molecular epidemiology of HIV is trending to be more complex. Thus, timely molecular epidemiologic supervision of HIV is necessary, especially for the MSM population.

show abstract

“…2 ). Importantly, however, migrants in Shenzhen had significantly different HIV-1 subtype distributions from MSM still living in their home regions (p < 0.01) 12 25 26 27 28 29 30 31 32 33 ( Fig. 2 ).…”

Section: Discussionmentioning

confidence: 97%

The dynamics of the HIV epidemic among men who have sex with men (MSM) from 2005 to 2012 in Shenzhen, China

Zhao

Chen

Chaillon

et al. 2016

Sci Rep

View full text Add to dashboard Cite

HIV-1 epidemics among MSM are a major public health concern in China, especially in large cities. This study sought to better understand the dynamics of HIV molecular epidemiology among MSM in Shenzhen, a rapidly developing city with over 13.8 million people. HIV-1 pol sequences were obtained from 996 (53.5%) of 1862 HIV-infected MSM and 403(9.0%) of 4498 heterosexuals and injection drug users in Shenzhen, China from 2005-2012. Eight HIV-1 subtypes and some inter-subtype recombinants were identified among sampled MSM with CRF07_BC (39.1%) and CRF01_AE (35.1%) being the most predominant. From 2006 to 2012, the prevalence of CRF07_BC and CRF55_01B rapidly increased, while the prevalence of subtypes B and CRF01_AE gradually decreased. The genetic distances within CRF07_BC and CRF55_01B groups were significantly lower than within CRF01_AE and B groups. The vast majority (90.3%) of HIV-1 infected MSM in Shenzhen were migrants who came from 31 of the 34 provinces of China, and these migrants had significantly different HIV-1 subtype distributions from the local MSM. This study highlighted the importance of CRF07_BC and migrants in the changing HIV epidemic among MSM in China, and provides a molecular epidemiology framework for understanding how HIV-1 epidemics can change in large cities with diverse risk groups.

show abstract

Subtype B Was the Dominant Strain Among HIV Type 1 Infections Except for the Population of Men Who Have Sex with Men in Harbin City, China

Cited by 9 publications

References 15 publications

HIV Prevention Services and Testing Utilization Behaviors among Men Who Have Sex with Men at Elevated Risk for HIV in Chongqing, China

HIV Prevention Services and Testing Utilization Behaviors among Men Who Have Sex with Men at Elevated Risk for HIV in Chongqing, China

Molecular epidemiology is becoming complex under the dynamic HIV prevalence: The perspective from Harbin, China

The dynamics of the HIV epidemic among men who have sex with men (MSM) from 2005 to 2012 in Shenzhen, China

Contact Info

Product

Resources

About