Subtotal Bilaterl Adrenalectomy for Hyper-Adrenalism (Essential Hypertensiox)

DeCourcy, Joseph L.

doi:10.1097/00000658-193408000-00006

Cited by 23 publications

(4 citation statements)

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“…The first case of a bilateral partial adrenalectomy in a human was described in 1934 by Decourcy for treatment of arterial hypertension [6]. In 1946, Broster performed partial adrenalectomies on bilateral tumors in a 9-year-old child affected with pseudohermaphroditism [7].…”

Section: Introductionmentioning

confidence: 99%

Minimally invasive cortical-sparing surgery for bilateral pheochromocytomas

Alesina

Hinrichs

Meier

et al. 2011

Langenbecks Arch Surg

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Section: Introductionmentioning

confidence: 99%

Minimally invasive cortical-sparing surgery for bilateral pheochromocytomas

Alesina

Hinrichs

Meier

et al. 2011

Langenbecks Arch Surg

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“…PA was first described in 1934 by De Courcy and then introduced in 1983 to treat familial bilateral PHEO by Irvin et al [ 10 , 20 , 39 ] Minimally-invasive approaches (PRA) to PA in PHEO patients were first reported by Walz et al [ 20 ] (1996), achieving good results in terms of surgical outcome and residual cortical function. In 2004, the same team also reported the largest series in the published literature with 100 laparoscopic PA procedures [ 36 , 40 ].…”

Section: Discussionmentioning

confidence: 99%

Outcome of Partial Adrenalectomy in MEN2 Syndrome: Personal Experience and Systematic Review of Literature

Procopio

Pennestrì

Crea

et al. 2023

Life

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Background: Partial adrenalectomy (PA) is an alternative option to total adrenalectomy for the treatment of hereditary pheochromocytoma (PHEO) to preserve cortical function and avoid life-long steroid replacement. The aim of this review is to summarize current evidence in terms of clinical outcome, recurrence, and corticosteroid therapy implementation after PA for MEN2-PHEOs. Material and Methods: From a total of 931 adrenalectomies (1997–2022), 16 of the 194 patients who underwent surgical treatment of PHEO had MEN2 syndrome. There were six patients scheduled for PA. MEDLINE®, EMBASE®, Web of Science, and Cochrane Library were searched for English studies from 1981 to 2022. Results: Among six patients who underwent PA for MEN2-related PHEO in our center, we reported two with bilateral synchronous disease and three with metachronous PHEOs. One recurrence was registered. Less than 20 mg/day Hydrocortison therapy was necessary in 50% of patients after bilateral procedures. Systematic review identified 83 PA for MEN2-PHEO. Bilateral synchronous PHEO, metachronous PHEO and disease recurrence were reported in 42%, 26%, and 4% of patients, respectively. Postoperative steroid implementation was necessary in 65% of patients who underwent bilateral procedures. Conclusions: PA seems to be a safe and valuable option for the treatment of MEN2-related PHEOs, balancing the risk of disease recurrence with the need for corticosteroid therapy.

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“…Moreover, they observed that the removal of three-quarters to seven-eighths of the adrenal tissue does not cause adrenal insufficiency ( 1 ). The first description of partial adrenalectomy in humans was published in 1934 based on the hypothesis that medullary adrenal hyperplasia is responsible for severe arterial hypertension and bilateral partial adrenalectomy might be its therapy ( 2 ). The operation that consisted in the removal of two-third to three-fourth of each adrenal was performed in two stages from the back through a “so-called” kidney incision under spinal anesthesia.…”

Section: Introductionmentioning

confidence: 99%

Tailored Approach in Adrenal Surgery: Retroperitoneoscopic Partial Adrenalectomy

et al. 2022

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The interest on partial adrenalectomy has steadily increased over the past twenty years. Adrenal pathologies are mostly benign, making an organ-preserving procedure attractive for many patients. The introduction of minimally invasive techniques played probably an important role in this process because they transformed a complex surgical procedure, related to the difficult access to the retroperitoneal space, into a simple operation improving the accessibility to this organ. In this review we summarize the role of partial retroperitoneoscopic adrenalectomy over the years and the current indications and technique.

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Subtotal Bilaterl Adrenalectomy for Hyper-Adrenalism (Essential Hypertensiox)

Cited by 23 publications

References 1 publication

Minimally invasive cortical-sparing surgery for bilateral pheochromocytomas

Minimally invasive cortical-sparing surgery for bilateral pheochromocytomas

Outcome of Partial Adrenalectomy in MEN2 Syndrome: Personal Experience and Systematic Review of Literature

Tailored Approach in Adrenal Surgery: Retroperitoneoscopic Partial Adrenalectomy

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