Abstract:The acyl-CoA dehydrogenase family enzyme DmdC catalyzes the third step in the dimethylsulfoniopropionate (DMSP) demethylation pathway, the oxidation of 3-methylmercaptopropionyl-CoA (MMPA-CoA) to 3-methylthioacryloyl-CoA (MTA-CoA). To study its substrate specificity, the recombinant DmdC1 from
Ruegeria pomeroyi
was characterized. In addition to MMPA-CoA, the enzyme was highly active with short chain acyl-CoAs, with
K
m
va… Show more
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