Abstract:24R ,25(OH) 2 D 3 ] is one of the major metabolites of vitamin D 3 , which is being examined as an anti-osteoporosis medicine 1 , and much interest is focused on the metabolism of 24R,25(OH) 2 D 3 . In a previous paper of this series, we reported the in vitro glucuronidation of 24R,25(OH) 2 D 3 using rat liver microsome as an enzyme source, in which its 3-and 24-glucuronides (G) were formed as the main products together with a small amount of the corresponding 25G. 2 On the other hand, we also reported that… Show more
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