Substitution of red meat with poultry or fish and risk of type 2 diabetes: a Danish cohort study

Ibsen, Daniel B; Warberg, Christine Kloster; Würtz, Anne Mette Lund; Overvad, Kim; Dahm, Christina C.

doi:10.1007/s00394-018-1820-0

Cited by 25 publications

(21 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Yet another surprising finding is that the effect of red meat is independent of animal fat or its most common saturated fatty acid, palmitic acid. The takehome message of the study is consistent with that of a recent report that fish intake relative to red meat, lowers the risk of type 2 diabetes, yet another chronic disease (11). Interestingly, with type 2 diabetes, poultry consumption showed protective effects not noted with endometriosis.…”

supporting

confidence: 88%

Seeing red: diet and endometriosis risk

Simmen

Kelley

2018

Ann. Transl. Med

View full text Add to dashboard Cite

supporting

confidence: 88%

Seeing red: diet and endometriosis risk

Simmen

Kelley

2018

Ann. Transl. Med

View full text Add to dashboard Cite

“…In 2010, a meta-analysis documented 19% higher diabetes risk per 50 g/day PRM, while URM does not reach significance [28]. Additionally, a study reported that replacing PRM with UPM reduced T2DM incidence (HR 0.96, 95% CI 0.93, 0.99) [51]. Factors which might help to explain the higher RR for PRM include higher saturated fatty acid, sodium, heme iron, and salt content [28,52,53], the aromatic hydrocarbons, heterocyclic amines and Advanced Glycation End Products (AGEs) that arise from hightemperature making-processing [54,55] and the nitrates-nitrites preservatives added in processing [52].…”

Section: Discussionmentioning

confidence: 99%

Processed and Unprocessed Red Meat Consumption and Risk for Type 2 Diabetes Mellitus: An Updated Meta-Analysis of Cohort Studies

Rui

Moore

et al. 2021

IJERPH

View full text Add to dashboard Cite

Type II diabetes mellitus (T2DM) is a metabolic disorder that occurs in the body because of decreased insulin activity and/or insulin secretion. The incidence of T2DM has rapidly increased over recent decades. The relation between consumption of different types of red meats and risk of T2DM remains uncertain. This meta-analysis was conducted to quantitatively assess the associations of processed red meat (PRM) and unprocessed red meat (URM) consumption with T2DM. We searched PubMed, Embase, Web of Science and The Cochrane Library for English-language cohort studies published before January 2021. Summary relative risks (RR) with 95% confidence interval (CI) were estimated using fixed effects and random effects. Additionally, dose–response relationships were explored using meta-regression. Fifteen studies (N = 682,963 participants, cases = 50,675) were identified. Compared with the lowest intake group, high consumption of PRM and URM increased T2DM risk by 27% (95% CI 1.15–1.40) and 15% (95% CI 1.08–1.23), respectively. These relationships were consistently strongest for U.S-based studies, though the effects of sex are inconclusive. In conclusion, PRM and URM are both positively associated with T2DM incidence, and these relationships are strongest in the U.S. reduction of red meat consumption should be explored as a target for T2DM prevention initiatives.

show abstract

“…Besides, rich in total fat, saturated fat and other potential nutritional components (41,42) , red meat may independently or synergistically interact with heme iron to affect glucose metabolism. Poultry and fish are health substitutions of red meat and processed meat to help decrease the risk of developing T2DM (43) . Red meat, especially fresh fatty pork, is the main component of total meat intake in China (44) , red meat was close to 76% of total meat in this study.…”

Section: Discussionmentioning

confidence: 99%

“…Besides, rich in total fat, saturated fat and other potential nutritional components (41,42) , red meat may independently or synergistically interact with haem Fe to affect glucose metabolism. Poultry and fish are health substitutions of red meat and processed meat to help decrease the risk of developing T2DM (43) .…”

Section: Discussionmentioning

confidence: 99%

Dietary iron intake and the risk of type 2 diabetes mellitus in middle-aged and older adults in urban China: a prospective cohort study

Wang

et al. 2020

Br J Nutr

View full text Add to dashboard Cite

The association between dietary iron intake and diabetes risk remains inconsistent. We aimed to explore the association of dietary iron intake and type 2 diabetes mellitus (T2DM) risk in middle-aged and older adults in urban China. This study used data from the Guangzhou Nutrition and Health Study (GNHS), an on-going community-based prospective cohort study. Participants were recruited from 2008 to 2013 in Guangzhou community. 2,696 participants aged 40-75 years without T2DM at baseline were included in data analyses, with a median of 5.6 (IQR: 4.1-5.9) years of follow-up. T2DM was identified by self-reported diagnosis, fasting glucose ≥7.0 mmol/L, or glycosylated hemoglobin ≥6.5%. Cox proportional hazard models were used to estimate HRs and 95%CIs. We ascertained 205 incident T2DM cases during 13,476 person-years. The adjusted HR for T2DM risk in the fourth quartile of heme iron intake was 1.92 (95%CI: 1.07, 3.46; P-trend=0.010), compared with the first quartile intake. These significant associations were found in heme iron intake from total meat (HR:2.74; 95%CI: 1.22, 6.15; P-trend=0.011) and heme iron intake from red meat (HR:1.86; 95%CI: 1.01, 3.44; P-trend=0.034), but not heme iron intake from processed meat, poultry or fish/shellfish. The association between dietary intake of total iron or nonheme iron with T2DM risk had no significance. Our findings suggested that higher dietary intake of heme iron (especially from red meat), but not total iron or nonheme iron, was associated with greater T2DM risk in middle-aged and older adults.

show abstract

Substitution of red meat with poultry or fish and risk of type 2 diabetes: a Danish cohort study

Abstract: Replacing processed red meat with poultry, replacing total or processed red meat with fish, and replacing processed red meat with unprocessed red meat were all associated with a lower risk of type 2 diabetes.

Cited by 25 publications

References 28 publications

Seeing red: diet and endometriosis risk

Seeing red: diet and endometriosis risk

Processed and Unprocessed Red Meat Consumption and Risk for Type 2 Diabetes Mellitus: An Updated Meta-Analysis of Cohort Studies

Dietary iron intake and the risk of type 2 diabetes mellitus in middle-aged and older adults in urban China: a prospective cohort study

Contact Info

Product

Resources

About