Substituted β-Cyclodextrins Interact with PAMAM Dendrimer–DNA Complexes and Modify Transfection Efficiency

Molecular recognition and adsorption equilibria in starburst dendrimers: gas structure and sensing via molecular theory

“…One of these structures, the starburst dendrimers, has found applications in molecular recognition [1], catalysts [1,2] and catalyst supports [3,4], drug delivery [5,6] and gene therapy carriers [6][7][8], surface modifiers [9] (tribology, and information storage) and electronic devices and antennae [10]. Our research focuses on the design of dendrimers for use in gas and chemical detection.…”

New applications of nanoparticles in cardiovascular imaging

“…. The contrast mechanism of nanoparticles (liposomes or emulsions) [6][7][8], dendrimers [9,10], viral constructs [11], buckeyballs [17], or various polymers [18,19] can hold paramagnetic or superparamagnetic metals, optically active compounds (e.g., fluorescent molecules), or radionuclides. These can be detected with standard imaging equipment i.e.…”

Molecular imaging, targeted therapeutics, and nanoscience

“…Planning for new clinical trials combined with informatics approaches to assess biomedical imaging technologies . Enhancement of cooperation among NIH, FDA, HCFA, and industry (both large and small businesses) to improve the speed with which new imaging technologies, probes, and contrast agents can be transferred into clinical practice such as nanoparticles (liposomes or emulsions) [Lanza et al, 1992[Lanza et al, , 1996a[Lanza et al, , 1996bSipkins et al, 1998], dendrimers [Wiener et al, 1994;Bryant et al, 1999], viral constructs [Bulte et al, 2001a], or various polymers [Ma et al, 2001;Roessler et al, 2001] can be loaded with large payloads ( Fig. 1) of imaging agents such as paramagnetic or supraparamagnetic metals, fluorophores, or radionuclides to enable detection with standard imaging equipment.…”

“…Some versions of polymers might be utilized as carriers of magnetic and therapeutic materials as well [Ma et al, 2001;Roessler et al, 2001]. Various transport ligands such as the retroviral ''tat'' protein have been coupled to these agents to promote cell uptake (e.g., CLIO's) [Kang et al, 2002;Wunderbaldinger et al, 2002].…”