Substituted N-(thieno[2,3-b]pyridine-3-yl)acetamides: synthesis, reactions, and biological activity

Alkyl 4-Aryl-6-amino-7- phenyl-3-(phenylimino)-4,7-dihydro- 3H-[1,2]dithiolo[3,4-b]pyridine-5-carboxylates: Synthesis and Agrochemical Studies

“…It is known that 3-aminothieno[2,3-b]pyridines, which can be considered as structural analogs of the prepared 3-imino-3H-[1,2]dithiolo[3,4-b]pyridines 15 , are reported to be effective herbicide safeners [ 42 , 43 ] and plant growth regulators [ 44 ]. We studied the efficiency of new 3-imino-3H-[1,2]dithiolo[3,4-b]pyridines as 2,4-D antidotes using sunflower seedlings using the reported procedure [ 42 ] (see also Materials and Methods).…”

“…It is known that 3-aminothieno[2,3-b]pyridines, which can be considered as structural analogs of the prepared 3-imino-3H-[1,2]dithiolo[3,4-b]pyridines 15 , are reported to be effective herbicide safeners [ 42 , 43 ] and plant growth regulators [ 44 ]. We studied the efficiency of new 3-imino-3H-[1,2]dithiolo[3,4-b]pyridines as 2,4-D antidotes using sunflower seedlings using the reported procedure [ 42 ] (see also Materials and Methods). The antidote effect A was determined as a ratio of the hypocotyl (or root) length of sunflower seedlings in the “herbicide + antidote” experiments to the length in the reference group (where the seedlings were treated with 2,4-D only) (Equation (1)): A = ( L exp / L ref ) × 100%, where L exp is an organ length (mm) in the group of seedlings treated with herbicide and antidote, and L ref is an organ length (mm) in the reference group of sunflower seedlings.…”

Synthesis of New Water-Soluble Bunte Salts Bearing Thieno[2,3-b]Pyridine-3-yl Substituents

“…3-Aminothienopyridines 1 could be easily N-acylated with ClCH2C(O)Cl to give corresponding chloroacetamides 2 [18]. The yields are given in the Table 1.…”

Synthesis and Analgesic Activity of New Heterocyclic Cyanothioacetamide Derivatives

“…One of the main directions of the use of thioamide 1 is the preparation of a wide range of S,Nheterocyclic compounds, the most important of which are 3-cyanopyridine-2(1H)-thiones 2 [5][6][7][8][9][10][11] (Scheme 1). Compounds 2 are a convenient scaffolds for the synthesis of a wide range of thieno [2,3-b]pyridines [12][13][14][15][16][17][18][19][20], thiazolo [3,2-a]pyridines [21][22][23][24][25][26][27][28][29], pyrido [2,1-b] [1,3,5]thiadiazines [30 -34], dipyrido[1,2-a:1'2'-e] [1,3,5,7]tetrazocines [35], pyrido [1,2-a] [1,3,5] triazines [36], isothiazolo [5,4-b]pyridines [37][38][39][40], and other bi-and polycyclic structures.…”