Abstract:Variation of the activation parameters for the aminolysis in the SN2, acyl-transfer, SNAr and AdN reactions offers an additive mechanistic tool for the studies of these reactions in solution. This approach uses the substituent effects on the benzene and pyridine rings to the variation of the activation parameters, X (X = H, S, G), in the above reactions in the frameworks of the Hammett-like equations in order to evaluate the resultant X reaction constants. The single linear dependences of the internal enthalpy… Show more
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