Substanzkonsum, Störungen durch Substanzkonsum und begleitende                     psychische Störungen bei Jugendlichen

Wiedmann, Melina Felicitas; Atzendorf, Josefine; Basedow, Lukas A.; Roessner, Veit; Golub, Yulia; Kuitunen‐Paul, Sören

doi:10.1024/1422-4917/a000846

Cited by 9 publications

(12 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It remains speculative why specifically MDMA was involved in coping activities as compared to other substances with anxiolytic and sedative effects such as alcohol (which is known from adult studies) or opiates with their potentially more symptom-relieving properties [ 57 ]. One issue is that alcohol is more available and more commonly used among adolescents in the study region compared to MDMA [ 58 ]. Its use might simply be much too high and prevalent in our sample, resulting in a ceiling effect that prevents us from detecting self-medicating patterns due to high use in non-self-medicating adolescents.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Coping motives mediate the relationship between PTSD and MDMA use in adolescents with substance use disorders

Basedow

Wiedmann

Roessner

et al. 2022

Addict Sci Clin Pract

Self Cite

View full text Add to dashboard Cite

Background Post-traumatic stress disorder (PTSD) and substance use disorders (SUDs) often co-occur in adolescent patients. Previous research has shown that these patients differ from SUD patients without PTSD in terms of their substance use patterns. In this study, we aimed to test whether substance use in this population is related to an attempt to self-medicate PTSD-related symptoms. Methods German adolescent patients (aged 13–18 years) at an outpatient clinic for SUD treatment, n = 111 (43% female), completed a self-designed questionnaire on use motives, a measure of PTSD-related experiences, and underwent a standardized psychiatric interview including structured substance use questions. Participants were subsequently classified as ‘no traumatic experiences (‘noTEs’ but SUD), ‘traumatic experiences but no current PTSD diagnosis’ (‘TEs’ with SUD), and ‘PTSD’ with SUD. After establishing a self-designed motive measurement through exploratory and confirmatory factor analyses, we calculated non-parametric group differences and a mediation analysis in a linear regression framework. Results The past-year frequency of MDMA use was highest in the PTSD group and lowest in the noTE group (H (2) = 7.2, p = .027, η2 = .058), but no differences were found for frequencies of tobacco, alcohol, cannabis, or stimulant use (all H ≤ 4.9, p ≥ .085, η2 ≤ .033). While controlling for sex, the three groups showed a similar pattern (highest in the PTSD group and lowest in the noTE group) for coping scores (F (103) = 5.77, p = .004, η2 = .101). Finally, mediation analyses revealed an indirect effect of coping score (b = 0.61, 95% CI [0.29, 1.58], p = .145) on the association between group membership and MDMA use frequency. Conclusions In adolescent SUD patients, we found an association of current PTSD and lifetime traumatic experiences with higher MDMA use that could be partially explained by substance use being motivated by an attempt to cope with mental health symptoms. This indicates a coping process involved specifically in MDMA use compared to the use of other psychoactive substances, possibly due to unique psychoactive effects of MDMA.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Opiates, on the other hand, may not have been encountered by these patients, may have been less available compared to MDMA or more difficult to afford on a regular basis in the study region. In fact, only 3 of 201 adolescent patients in our institution reported any opiate use in the 12 months before admission [ 58 ].…”

Section: Discussionmentioning

confidence: 99%

Coping motives mediate the relationship between PTSD and MDMA use in adolescents with substance use disorders

Basedow

Wiedmann

Roessner

et al. 2022

Addict Sci Clin Pract

Self Cite

View full text Add to dashboard Cite

show abstract

“…Our results indicate that, in adolescent patients that report APS and co-occurring substance use, an assessment of TEs and PTSD is always indicated for a proper differential diagnosis. An integrated treatment of PTSD and SUD is not only warranted given the high comorbidity (Kuitunen-Paul et al, 2021 ; Wiedmann, Atzendorf, et al, 2022 ), it may also be possible, albeit this hast to be tested, that that APS might be indirectly alleviated by an integrated treatment of SUD and PTSD. A psychotherapeutic approach integrating therapy for symptoms from different disorders is even more important, given that pharmacological treatment options for either of these disorders and symptoms are heavily limited (Cohen et al, 2010 ).…”

Section: Discussionmentioning

confidence: 99%

“…However, APS are diagnostically diverse and adolescents with SUD also present with other mental disorder (Kuitunen-Paul et al, 2021 ; Wiedmann, Atzendorf, et al, 2022 ), thus it is possible that co-occurrence of SUD and APS might be related to yet another factor.…”

Section: Introductionmentioning

confidence: 99%

Attenuated psychotic symptoms, substance use and self-reported PTSD in adolescence

Basedow

Wiedmann

Kuitunen‐Paul

et al. 2023

European Journal of Psychotraumatology

Self Cite

View full text Add to dashboard Cite

Background: The occurrence of attenuated psychotic symptoms (APS) is a major concern in populations with substance use disorders (SUDs). However, APS also frequently develop in the course of Post-Traumatic Stress Disorder (PTSD). This study explores how the prevalence of APS differs between adolescent patients with only SUD, SUD with a history of traumatic experiences (TEs), and with SUD and self-reported PTSD. Methods: We recruited n = 120 treatment-seeking adolescents at a German outpatient clinic for adolescents with SUD. All participants filled out questionnaires assessing APS (PQ-16, YSR schizoid scale), trauma history, PTSD symptoms (both UCLA PTSD Index), and SUD severity (DUDIT) next to an extensive substance use interview. We performed a multivariate analysis of co-variance with the four PQ-16 scales and the YSR scale as outcomes and PTSD status as predictor. Additionally, we performed five linear regressions predicting each PQ-16 score and YSR score based on tobacco, alcohol, cannabis, ecstasy, amphetamine, and methamphetamine use. Results: Participants with co-occurring SUD and self-reported PTSD showed significantly higher APS prevalence rates (PQ-16 score, p = .00002), more disturbed thought content ( p = .000004), more perceptual disturbances ( p = .002), more negative symptoms ( p = .004) and more thought problems ( p = .001) compared to adolescents with SUD and a history of trauma and adolescents with only SUD. Past-year substance use was not predictive for APS prevalence ( F (75) = 0.42; p = .86; R 2 = .04). Conclusion: Our data suggests that the occurrence of APS in adolescents with SUD is better explained by co-occurring self-reported PTSD than by substance use frequency or substance class. This finding might indicate that APS might be reduced through treating PTSD or focusing on TEs in SUD therapy.

show abstract

“…Opioide, insbesondere als Konsum von Heroin, sind in großstädtischen Straßen-Drogenszenen sehr relevant, betreffen aber eher Erwachsene 7 . Eine Auswertung der Inanspruchnahmedaten in einer großstädtischen Spezialambulanz 10 zeigt, dass in der Behandlung von Suchtstörungen des Kindes- und Jugendalters neben cannabis- und alkoholbezogen Störungen (84 bzw. 52 % der Diagnosen) auch Störungen im Zusammenhang mit dem Konsum von Stimulanzien (45 %) häufig sind.…”

Section: Versorgungssituationunclassified

Sucht und Drogen bei Jugendlichen – State of the Art

Arnaud,

Thomasius

2023

PiD - Psychotherapie im Dialog

View full text Add to dashboard Cite

Jugendliche und junge Erwachsene sind besonders häufig von Suchtstörungen und begleitenden Problemen betroffen. In der Psychotherapie und in der empirischen Therapieforschung werden entwicklungsorientierte Konzepte der Suchtbehandlung bisher zu wenig berücksichtigt. Dieser Beitrag informiert über Epidemiologie, Entstehungsbedingungen, Diagnostik und Therapie der Suchtstörungen im Jugendalter.

show abstract

Substanzkonsum, Störungen durch Substanzkonsum und begleitende psychische Störungen bei Jugendlichen

Cited by 9 publications

References 53 publications

Coping motives mediate the relationship between PTSD and MDMA use in adolescents with substance use disorders

Coping motives mediate the relationship between PTSD and MDMA use in adolescents with substance use disorders

Attenuated psychotic symptoms, substance use and self-reported PTSD in adolescence

Sucht und Drogen bei Jugendlichen – State of the Art

Contact Info

Product

Resources

About