Substance-Related and Addictive Disorders

Grimaldi, John A.; Bodnar, John; Lavin, Daniel; McLaughlin, Michael L.; Rasimas, Joseph J.; Ashley, Kenneth

doi:10.1176/appi.books.9781585625031.rh23

Cited by 2 publications

(2 citation statements)

References 151 publications

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“…The known common side effects of hallucinogens include transient paranoia, mood changes, anxiety, sleep disturbances, headaches, and memory deficits. 1,37 In the studies discussed in this review, the most common side effects reported were acute increases in blood pressure and vomiting. Although a few instances of mood irritability did occur, these were able to be resolved by the treatment team.…”

Section: Discussionmentioning

confidence: 93%

Hallucinogens and Their Therapeutic Use: A Literature Review

Begola

Schillerstrom

2019

Journal of Psychiatric Practice

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All studies were considered for downgrade if they exhibited poor design, insufficient number of subjects (N < 10), or other methodological flaws. Studies not meeting the above criteria, including case reports and expert opinion papers, were excluded entirely. Adapted with permission from the The Oxford Levels of Evidence 2 developed by the Oxford Centre for Evidence-Based Medicine (https://www.cebm.net/index.aspx?o=5653) and from Ishii 2015. 30

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Section: Discussionmentioning

confidence: 93%

Hallucinogens and Their Therapeutic Use: A Literature Review

Begola

Schillerstrom

2019

Journal of Psychiatric Practice

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“…It is notable that dehydration state, which is frequently observed in acute methamphetamine intoxication state (Kosten et al, 2012), might be related to brain atrophic changes and ventricular enlargements (Dickson et al, 2005; Duning et al, 2005; Kempton et al, 2009, 2011a,b; Streitburger et al, 2012). Although the current methamphetamine-dependent subjects had a period of abstinence of at least 4 weeks, a subclinical and prolonged dehydration state related to chronic methamphetamine use may be partly responsible for lateral ventricular enlargement in this sample.…”

Section: Discussionmentioning

confidence: 99%

Morphometric abnormalities of the lateral ventricles in methamphetamine-dependent subjects

Jeong

Lee

Yoon

et al. 2013

Drug and Alcohol Dependence

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Background The presence of morphometric abnormalities of the lateral ventricles, which can reflect focal or diffuse atrophic changes of nearby brain structures, is not well characterized in methamphetamine dependence. The current study was aimed to examine the size and shape alterations of the lateral ventricles in methamphetamine-dependent subjects. Methods High-resolution brain structural images were obtained from 37 methamphetamine-dependent subjects and 25 demographically matched healthy individuals. Using a combined volumetric and surface-based morphometric approach, the structural variability of the lateral ventricles, with respect to extent and location, was examined. Results Methamphetamine-dependent subjects had an enlarged right lateral ventricle compared with healthy individuals. Morphometric analysis revealed a region-specific pattern of lateral ventricular expansion associated with methamphetamine dependence, which was mainly distributed in the areas adjacent to the ventral striatum, medial prefrontal cortex, and thalamus. Conclusions Patterns of shape decomposition in the lateral ventricles may have relevance to the structural vulnerability of the prefrontal-ventral striatal-thalamic circuit to methamphetamine-induced neurotoxicity.

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Substance-Related and Addictive Disorders

Cited by 2 publications

References 151 publications

Hallucinogens and Their Therapeutic Use: A Literature Review

Hallucinogens and Their Therapeutic Use: A Literature Review

Morphometric abnormalities of the lateral ventricles in methamphetamine-dependent subjects

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