Substance P/calcitonin gene‐related peptide and their receptors expression in human periodontal ligament after root canal preparation with five different systems
Javier Caviedes‐Bucheli,
Hernan Dario Muñoz‐Alvear,
Luis Fernando Lopez‐Moncayo
et al.
Abstract:AimThe purpose of this study was to quantify the effect of five different root canal preparation instruments on Substance P (SP), Calcitonin gene‐related peptide (CGRP) and their receptors expression in healthy human periodontal ligament.MethodologySTROBE guidelines were used to design a study using 60 periodontal ligament samples obtained from healthy lower premolars where extraction was indicated for orthodontic reasons. Prior to extraction 40 of these premolars were equally divided into four groups and root… Show more
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