Subspecificities of Australia antigen

Sama, Sonu; Krishnamurthy, Lisa C.; Gurdeep, Singh

doi:10.1007/bf01072740

Cited by 3 publications

(1 citation statement)

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“…Salzano e col. 27 , numa população de 633 indivíduos normais, encontraram 0,5% positivos para o antígeno Austrália. Considerados nossos resultados do ponto de vista das subespecificidades identificadas e sua distribuição segundo o tipo clínico da doença, parece ser evidente uma discordância com os achados de outros autores, que referem maior freqêüncia de encontro de HB s Ag em formas "Virch-wianas" 4,2,3, 13,27 , com predominância do subtipo ay 22,25,28 ; em nossos achados só foi identificado o subtipo ad com predomínio nas formas tuberculóides. O número muito restrito de observações pode explicar esta diferença em relação ao subtipo predominante, como em relação ao tipo de hanseníase.…”

Section: Discussão E Conclusõesunclassified

Subtipos do antígeno Austrália (HBsAg) em doentes de hanseníase de São Paulo, Brasil

Ottati

Candeias

1979

Rev. Saúde Pública

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Section: Discussão E Conclusõesunclassified

Subtipos do antígeno Austrália (HBsAg) em doentes de hanseníase de São Paulo, Brasil

Ottati

Candeias

1979

Rev. Saúde Pública

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Hepatitis B Virus Antigen: Validation and Immunologic Characterization of Low-Titer Serums with ¹²⁵ I-Antibody

Ling

Irace

Decker

et al. 1973

Science

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Radioimmunnoassay was used to determine the serologic subspecificities of 85 blood donor serums positive for hepatitis B virus-associated antigen. There was complete agreement with results obtained by immunoprecipitatiotn of 43 serums. The remaining 42 serums were negative by immunoprecipitation but followed type-specific immunology by radioimmunoassay, and this served as a validation for authentic hepatitis B virus antigen.

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Some Epidemiological and Clinical Aspects of Hepatitis B Antigen and Its Subtypes

Nordenfelt

1975

Scandinavian Journal of Infectious Diseases

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The close association between hepatitis B antigen (HBAg) and the infectious agent of hepatitis B is clear. Many investigations have shown HBAg to be a useful tool for epidemiological studies of hepatitis B. The relation between HBAg and the postulated hepatitis B virus (HBV) is as yet not clear. In light of recent results a possible candidate could be the so-called Dane particle, which has HBAg reactivity on the surface, but possesses an antigenically distinct core. The core has been shown to have associated DNA polymerase activity. The particles which carry HBAg reactivity have surfaces which are antigenically complex. One common specificity a and 2 pairs of mutually exclusive determinants have been recognized namely d and y and w and r but further possible specificities are under investigation. Four different phenotypes have been described, adw, adr, ayw and ayr. Present evidence indicates that adw, adr and ayw are the phenotypic expression of 3 different transmissible strains of HBV. Studies on the epidemiology of these subtypes have shown 3 different geographic patterns. In the USA and Northern Europe both Dw (adw) and YW (ayw) are common, but in the Eastern Mediterranean and Middle East Yw is practically the only type found. In the Far East DR (adr) is the dominating subtype. Investigations have been done to determine whether there are any clinical differences in hepatitis caused by the different tubtypes. No certain differences have been shown.

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Subspecificities of Australia antigen

Cited by 3 publications

References 13 publications

Subtipos do antígeno Austrália (HBsAg) em doentes de hanseníase de São Paulo, Brasil

Subtipos do antígeno Austrália (HBsAg) em doentes de hanseníase de São Paulo, Brasil

Hepatitis B Virus Antigen: Validation and Immunologic Characterization of Low-Titer Serums with ¹²⁵ I-Antibody

Some Epidemiological and Clinical Aspects of Hepatitis B Antigen and Its Subtypes

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Subspecificities of Australia antigen

Cited by 3 publications

References 13 publications

Subtipos do antígeno Austrália (HBsAg) em doentes de hanseníase de São Paulo, Brasil

Subtipos do antígeno Austrália (HBsAg) em doentes de hanseníase de São Paulo, Brasil

Hepatitis B Virus Antigen: Validation and Immunologic Characterization of Low-Titer Serums with 125 I-Antibody

Some Epidemiological and Clinical Aspects of Hepatitis B Antigen and Its Subtypes

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Product

Resources

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Hepatitis B Virus Antigen: Validation and Immunologic Characterization of Low-Titer Serums with ¹²⁵ I-Antibody