Subperiosteal Schwannoma ; A Single Center Experience in India

Subperiosteal Schwannoma of the Mid-Tibia: A Cause of Long-Lasting Unexplained Pain

“…Imaging is the most important diagnostic tool for the evaluation of patients with suspected schwannomas [15]; the radiographs can help in localizing the lesion with subperiosteal or intraosseous localization. The radiographic appearances of periosteal schwannomas mentioned in the available case reports are variable; the most constant feature is the presence of a lytic lesion, which was mentioned in nearly all reported cases including our case [4,5,7,8]. Patro et al have reported a unique case of subperiosteal schwannoma with normal-appearing radiographs despite the long and extended course of their patient's disease (two years) [6].…”

“…The second case was reported by Singh et al in 2005, when they reported a subperiosteal schwannoma arising from the surface of the diaphysis of the ulna in a 28-year-old female patient that showed up as painful swelling [5]. Afterward, only three more case reports of this disease have been published: in 2014, 2016, and 2020 [6][7][8]. Pain was a constant and chief complaint in all reported cases, and most patients had delayed diagnosis.…”

“…It is a rare condition and usually occurs in soft tissues [3]. In extremely rare cases, schwannomas can present on the bone surface as subperiosteal neoplasm, and this rare condition has been described and reported in only five documented cases so far [4][5][6][7][8]. Herein, we present the sixth case report documenting this rare condition.…”