Suboptimal health pregnant women are associated with increased oxidative stress and unbalanced pro- and antiangiogenic growth mediators: a cross-sectional study in a Ghanaian population

Anto, Enoch Odame; Roberts, Peter; Coall, David A.; Adua, Eric; Turpin, Cornelius Archer; Tawiah, Augustine; Wang, Youxin; Wang, Wei

doi:10.1080/10715762.2019.1685668

Cited by 29 publications

(28 citation statements)

References 34 publications

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“…Lastly, the SHSQ-25 is only a subjective instrument and does not provide any objective information. Our previous studies have revealed the association between SHS and objective markers of chronic diseases including the increases of blood pressure, lowdensity lipoproteins plasma cortisol and mRNA expression of glucocorticoid receptor α/β in lymphocyte (10) and blood glucose (9,18,19), endothelial dysfunction (7), and also pregnancy-related disorders (15). Going forward, our research will seek to unravel and discern the link between SHS and objective biomarkers of dysfunctional immune, mental, cardiovascular and the digestive systems.…”

Section: Discussionmentioning

confidence: 96%

“…Among Chinese youths, SHS was associated with altered intestinal microbiota (17). Furthermore, its association with objective markers including plasma cortisol, mRNA expression of glucocorticoid receptor α/β (10), plasma metabolites (13), N-glycosylation pro les (14), telomere length (18) and oxidative stress (19) as well as angiogenic growth mediators (19) have been reported.…”

Section: Introductionmentioning

confidence: 98%

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Construct Validity of the Suboptimal Health Status Questionnaire-25 in a Ghanaian Population

Adua

Afrifa-Yamoah

Frimpong

et al. 2020

Preprint

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Background: The Suboptimal Health Status Questionnaire-25 (SHS-Q-25) developed to measure suboptimal health status has been used worldwide, but its construct validity has only been tested in the Chinese population. In this article, we investigate aspects of the construct validity of the SHS-Q-25 to determine the interactions between SHS subscales in a Ghanaian population. Methods: The study involved healthy Ghanaian participants (n = 263; aged 20-80 years; 63% female), who responded to the SHSQ-25. In an exploratory factor and parallel analysis, the study extracted a new domain structure and compared to the established five-domain structure of SHSQ-25. A confirmatory factor analysis (CFA) was conducted and the fit of the model further discussed. Invariance analysis was carried out to establish the consistency of the instrument across multi-groups. Results: The extracted domains were reliable with Cronbach’s of 0.861, 0.821 and 0.853 respectively, for fatigue, immune-cardiovascular and cognitive, confirming the construct validity of the SHSQ-25 instrument. The CFA revealed that the model fit indices were excellent but the fit indices for the three-domain model were statistically superior to the five-domain model. There were, however, issues of insufficient discriminant validity as some average variance extracts (AVE) were smaller than the corresponding maximum shared variance (MSV). The three-domain model was invariant for all constrained aspects of the structural model across age, which is an important risk factor for most chronic diseases. Conclusion: The validity tests provide evidence to endorse the credibility of the tool and suggest that the SHS-Q25 can measure SHS in a Ghanaian population. It can be recommended as a screening tool to early detect possible for chronic diseases especially in developing countries where the access to facilities is diminished.

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Section: Discussionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 98%

Construct Validity of the Suboptimal Health Status Questionnaire-25 in a Ghanaian Population

Adua

Afrifa-Yamoah

Frimpong

et al. 2020

Preprint

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Construct Validity of the Suboptimal Health Status Questionnaire-25 in a Ghanaian Population

Adua

Afrifa-Yamoah

Frimpong

et al. 2020

Preprint

Self Cite

View full text Add to dashboard Cite

Background: The Suboptimal Health Status Questionnaire-25 (SHS-Q-25) developed to measure suboptimal health status has been used worldwide, but its construct validity has only been tested in the Chinese population. In this article, we investigate aspects of the construct validity of the SHS-Q-25 to determine the interactions between SHS subscales in a Ghanaian population.Methods: The study involved healthy Ghanaian participants (n = 263; aged 20-80 years; 63% female), who responded to the SHSQ-25. In an exploratory factor and parallel analysis, the study extracted a new domain structure and compared to the established five-domain structure of SHSQ-25. A confirmatory factor analysis (CFA) was conducted and the fit of the model further discussed. Invariance analysis was carried out to establish the consistency of the instrument across multi-groups. Results: The extracted domains were reliable with Cronbach’s B of 0.861, 0.821 and 0.853 respectively, for fatigue, immune-cardiovascular and cognitive, confirming the construct validity of the SHSQ-25 instrument. The CFA revealed that the model fit indices were excellent a The fit indices for the three-domain model were statistically superior to the five-domain model. There were, however, issues of insufficient discriminant validity as some average variance extracts (AVE) were smaller than the corresponding maximum shared variance (MSV). The three-domain model was invariant for all constrained aspects of the structural model across age, which is an important risk factor for most chronic diseases.Conclusion: The validity tests provide evidence to endorse the credibility of the tool and suggest that the SHS-Q25 can measure SHS in a Ghanaian population. It can be recommended as a screening tool to early detect possible for chronic diseases especially in developing countries where the access to facilities is diminished.

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“…In traditional Chinese medicine (TCM) guidelines released by the China Association of Chinese Medicine, SHS is characterized as a decline in vitality, physiological function and the capacity for social adaptation, with no clear disease in clinical diagnosis [1]. The concept of SHS has been widely accepted in some other countries, including Japan, Ghana and Australia [2,3], but it has not been clearly used in western countries. It seems that chronic fatigue is a more common concern in western countries, which is an individualized feeling of weakness, lack of energy and burnout, including physical and mental fatigue [4].…”

Section: Introductionmentioning

confidence: 99%

“…SHS is becoming a global health issue. The SHS prevalence took up 71.7% in nurses [8], 69.46% in Chinese adults [9] and 55.9% in Chinese students [10], and SHS had adverse effects on metabolic syndrome [3], cognitive impairment [7], oxidative stress in pregnant women [2]. Thus, it might be of great importance for medicine staff to early detect and prevent SHS resulting in chronic disease and other adverse impacts.…”

Section: Introductionmentioning

confidence: 99%

Psychometric Properties of The Sub-Health Measurement Scale V1.0 for Assessing Suboptimal Health Status of Midwives: A Multi-Centre Cross-Sectional Study

Chen

Jiang²,

Zheng

et al. 2020

Preprint

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Purpose Midwives with high work stress are prone to suboptimal health status (SHS). However, there is a lack of unified measurement standard for SHS. Sub-Health Measurement Scale V1.0 (SHMS V1.0) is a multidimensional inventory that has been proved to have adequate psychometric properties in other populations. Therefore, this study aimed to evaluate validity and reliability of SHMS V1.0 in midwives.Methods In this cross-sectional study, 842 midwives from 46 midwifery institutions completed the SHMS V1.0. Internal consistency and test-retest reliability of SHMS V1.0 were assessed with Cronbach's alpha and Pearson correlation coefficient. Project analysis and confirmatory factor analysis (CFA) were performed to assess construct validity. Concurrent validity of SHMS V1.0 was evaluated by Pearson correlation analysis with the 14-item Fatigue Scale (FS-14).Results The total Cronbach's alpha and test-retest reliability coefficient of SHMS V1.0 was 0.908 and 0.804, respectively. The correlation coefficients between each item and its corresponding dimension, and those between each dimension and its corresponding subscale were all greater than 0.4. The CFA supported the structure of SHMS V1.0 with strong factor loadings and excellent fit indexes in the first-order and modified second-order factor model. The concurrent validity for SHMS V1.0 showed large correlation with FS-14, but social subscale showed medium correlations with total fatigue, physical fatigue and mental fatigue. Conclusions The SHMS V1.0 is a valid and reliable instrument for measuring SHS for midwives. Given the severity and harmfulness of SHS in midwives, SHMS V1.0 is recommended as an important tool for clinical practice and research.

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Suboptimal health pregnant women are associated with increased oxidative stress and unbalanced pro- and antiangiogenic growth mediators: a cross-sectional study in a Ghanaian population

Cited by 29 publications

References 34 publications

Construct Validity of the Suboptimal Health Status Questionnaire-25 in a Ghanaian Population

Construct Validity of the Suboptimal Health Status Questionnaire-25 in a Ghanaian Population

Construct Validity of the Suboptimal Health Status Questionnaire-25 in a Ghanaian Population

Psychometric Properties of The Sub-Health Measurement Scale V1.0 for Assessing Suboptimal Health Status of Midwives: A Multi-Centre Cross-Sectional Study

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