Submerged Culture Fermentation, Factors Affecting the Production of Ustilagic Acid by Ustilago Zeae

Cellobioselipide und Mannosylerythritollipide sind viel versprechende Glykolipide mit Tensid- Eigenschaften, die bisher jedoch unzureichend für Anwendungszwecke z. B. als Zusatz von Reinigungs- und Körperpflegemitteln charakterisiert wurden. Durch gezielte Anpassung der Kultivierungs- und Prozessführungsstrategien wurde die getrennte Herstellung von Cellobioselipiden und Mannosylerythritollipiden aus Ustilago maydis untersucht und optimiert

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“…Glucose ist die meist genutzte hydrophile C-Quelle für die Synthese von Cellobioselipiden mit U. maydis [11,15] …”

Section: Einfluss Der C-quelle Auf Die Cl-synthese Mit Ruhenden Zellenunclassified

Synthese und Optimierung von Cellobioselipiden und Mannosylerythritollipiden

Rupp

Zibek

Günther

et al. 2010

Chemie Ingenieur Technik

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“…Other investigators have made simil observations. In their studies on ustilagic acid formation, Sallans, Roxburgh, and Spencer (96) found that to achieve the same productivity in shake-flasks with KLa = 90 (29) and in stirred fermenters, the latter had to be operated at KLa -600. The values given for KLa in table 4 must therefore be interpreted cautiously when applied to product formation rather than to oxygen uptake.…”

Section: ]mentioning

confidence: 99%

Agitation-Aeration in the Laboratory and in Industry

Finn¹

1954

Bacteriological Reviews

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“…The active principle of U. maydis was named ustilagic acid and was found to be a secreted glycolipid, which is toxic for a variety of prokaryotic and eukaryotic microorganisms (Haskins and Thorn, 1951;Reed and Holder, 1953). Although initial attempts were already started for fermentation of ustilagic acid in large-scale (Roxburgh et al, 1954), further investigations revealed that the potential use of ustilagic acid for medical and therapeutical purposes was limited due to instability of this drug if administered orally.…”

Section: Introductionmentioning

confidence: 99%