Subjective, functional and microbiological parameters of the oral cavity in gastroesophageal reflux patients with acidic and subacidic refluctant

Abstract

The aim of the study was to compare dental and periodontal status, oral hygiene, salivation rate, functional parameters of saliva and oral microbiota composition in patients with gastroesophageal reflux disease (GERD) with acidic and subacidic refluctant. The study comprised 69 participants divided in 3 groups: 22 healthy volunteers (controls) and 2 main groups: 25 GERD patients with acidic (group 2) and 22 patients with subacidic refluctant (group 3). Poor dental and periodontal condition was revealed in group 3 patients probably because of aggressive intestinal content reflux in the oral cavity resulting in higher PMA an saliva pH values, Escherichia coli species in oral microbiota and low buffer capacity of saliva. The results show that GERD may be suspected due to oral manifestations thus promoting it's prompt treatment.

Comparison of the Microbiota and Inorganic Anion Content in the Saliva of Patients with Gastroesophageal Reflux Disease and Gastroesophageal Reflux Disease-Free Individuals

“…In individuals with GERD, the gastric content may return to the esophagus and reach the oral cavity leading to dental erosions and carious lesions. Such manifestations of GERD can also impact on the oral bacterial community structure [15]. Therefore, it is imperative to investigate differences in the composition of the microbiota and inorganic anions in the saliva of patients with GERD.…”

“…Dental erosion by stomach acids may be another sign of GERD in people who have not yet experienced typical symptoms [12,13]. Such manifestations of the disease can also influence on the oral microbial community structure [14,15]. However, despite the importance of oral microbiota analysis, little attention has been paid to the characterization of the salivary microbiota in people with gastroesophageal reflux disease, which might affect the microbial community structure.…”