Subjective and objective quality of life, levels of life skills, and their clinical determinants in outpatients with schizophrenia

Aki, Hirofumi; Tomotake, Masahito; Kaneda, Yasufumi; Iga, Jun‐ichi; Kinouchi, Sawako; Shibuya-Tayoshi, Sumiko; Tayoshi, ShinʼYa; Motoki, Ikuyo; Moriguchi, Kazuhiko; Sumitani, Satsuki; Yamauchi, Ken; Taniguchi, Takahide; Ishimoto, Yasuhito; Ueno, Shu‐ichi; Ohmori, Tetsuro

doi:10.1016/j.psychres.2006.05.017

Cited by 65 publications

(56 citation statements)

References 32 publications

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“…Verbal memory has been reported to be important cognitive domain that affects social function [5] [6] [19] [20]. In addition, depressive symptoms have been found to affect schizophrenia patient's quality of life and life skills [21]- [23]. The present results also suggest that depressive symptom is an important variable for employment.…”

Section: Discussionsupporting

confidence: 61%

Relationship between Cognitive Function and Employment in Japanese Schizophrenia Patients

Takeda¹,

Tomotake²,

Ueoka³

et al. 2016

OJPsych

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The purpose of the present study was to examine the relationship between cognitive function and employment in Japanese schizophrenia patients. Subjects were 61 outpatients. Cognitive function was assessed using the Brief Assessment of Cognition in Schizophrenia. Clinical symptoms were also evaluated with the Positive and Negative Syndrome Scale and the Calgary Depression Scale for Schizophrenia. Verbal memory (F(1, 58) = 5.50, p = 0.02) and attention and speed of information processing scores (F(1, 58) = 4.92, p = 0.03) showed significant differences between employment and unemployment groups. Logistic regression analysis showed that employment was significantly predicted by verbal memory (x 2 = 16.09, df = 2, p = 0.01) and depression scores (x 2 = 16.09, df = 2, p = 0.02). The results suggest that improving verbal memory and depression may lead to employment in Japanese schizophrenia patients.

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Section: Discussionsupporting

confidence: 61%

Relationship between Cognitive Function and Employment in Japanese Schizophrenia Patients

Takeda¹,

Tomotake²,

Ueoka³

et al. 2016

OJPsych

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“…The present study is of clinical importance in showing that both an observer-rated (objective) and self-rated (subjective) QOL measures were improved after QTP therapy. It has been shown that objective QOL scale such as QLS and subjective QOL scale such as SQLS show poor correlation and different symptomatic determinant (Aki et al, 2006). QLS, which has been most often used in the previous QOL studies, was originally developed for a measurement of deficit symptoms of schizophrenia (Heinrichs et al, 1984).…”

Section: Discussionmentioning

confidence: 99%

“…QLS, which has been most often used in the previous QOL studies, was originally developed for a measurement of deficit symptoms of schizophrenia (Heinrichs et al, 1984). It is with reason that QLS scores correlate with negative symptom scores (Dickerson et al, 1998;Fitzgerald et al, 2001;Aki et al, 2006). In contrast, subjective QOL scale scores such as SQLS have been reported to correlate not with negative symptoms but with depressive symptoms (Wilkinson et al, 2000;Aki et al, 2006) and positive symptoms (Tomotake et al, unpublished observation).…”

Section: Discussionmentioning

confidence: 99%

“…Some recent studies have measured self-rated subjective QOL (Franz et al, 1997;Tempier and Pawliuk, 2001;Kilian et al, 2004). However, studies including our own (Dickerson et al, 1998;Fitzgerald et al, 2001;Aki et al, 2006) pointed out that objective and subjective QOL scale scores show poor correlation and different symptomatic determinants. A recent cross-sectional study showed that self-rated QOL scores did not reflect observer-rated measures of QOL (Voruganti et al, 2000).…”

Section: Introductionmentioning

confidence: 93%

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Effect of antipsychotic replacement with quetiapine on the symptoms and quality of life of schizophrenic patients with extrapyramidal symptoms

Taniguchi

Sumitani

Aono

et al. 2006

Human Psychopharmacology

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Replacement of antipsychotic drugs with quetiapine (QTP) was tried in a naturalistic setting in chronic schizophrenic patients who still showed moderate psychiatric symptoms and either showed extrapyramidal symptoms (EPS) or took anti-parkinson drugs for the EPS. QTP was added on and gradually increased while the previous drugs were tapered and discontinued whenever possible. Clinical symptoms, objective and subjective QOL, and EPS were measured before and 6 months after QTP addition, using Brief Psychiatric Rating Scale (BPRS), Quality of Life Scale (QLS), Schizophrenia Quality of Life Scale (SQLS) and Drug-Induced Extrapyramidal Symptom Scale (DIEPSS), respectively. Twenty-one patients completed the trial and received the assessment. It was found that replacement with QTP-improved clinical symptoms, objective and subjective QOL and EPS. This improvement was equally observed in not only patients who switched to QTP monotherapy (n = 11) but also patients who took QTP together with reduced small doses (4.4 +/- 4.3 mg/day) of previous drugs (n = 11). The results suggest that replacement with QTP improves symptoms as well as objective and subjective QOL in a subgroup of schizophrenia.

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“…Recently, Aki et al (22) investigated the relation between life skills and QOL in schizophrenia patients. In the study, they used the Life Skills Profile (LSP) to evaluate life skills of patients with schizophrenia, and subjective QOL and objective QOL were assessed the SQLS and the QLS, respectively.…”

Section: Relation Between Life Skills and Quality Of Lifementioning

confidence: 99%

Quality of life and its predictors in people with schizophrenia

Tomotake

2011

J. Med. Invest.

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Subjective and objective quality of life, levels of life skills, and their clinical determinants in outpatients with schizophrenia

Cited by 65 publications

References 32 publications

Relationship between Cognitive Function and Employment in Japanese Schizophrenia Patients

Relationship between Cognitive Function and Employment in Japanese Schizophrenia Patients

Effect of antipsychotic replacement with quetiapine on the symptoms and quality of life of schizophrenic patients with extrapyramidal symptoms

Quality of life and its predictors in people with schizophrenia

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