Subject‐specific loads on the lumbar spine in detailed finite element models scaled geometrically and kinematic‐driven by radiography images

Dehghan-Hamani, Iraj; Arjmand, Navid; Shirazi‐Adl, A.

doi:10.1002/cnm.3182

Cited by 17 publications

(16 citation statements)

References 47 publications

(116 reference statements)

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“…The disc pressure was approximately constant in the NP, and the mechanical response was governed mainly by the fluid pressure. This observation justified the use of cavity models in some studies to simulate the NP [27,47,64]. The predicted IDP in the NP under flexion and extension showed good agreement with the in vitro data measured by pressure transducers [63] (Fig.…”

Section: Discussionsupporting

confidence: 78%

The importance of intervertebral disc material model on the prediction of mechanical function of the cervical spine

Komeili

Rasoulian

Moghaddam

et al. 2021

BMC Musculoskelet Disord

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Background Linear elastic, hyperelastic, and multiphasic material constitutive models are frequently used for spinal intervertebral disc simulations. While the characteristics of each model are known, their effect on spine mechanical response requires a careful investigation. The use of advanced material models may not be applicable when material constants are not available, model convergence is unlikely, and computational time is a concern. On the other hand, poor estimations of tissue’s mechanical response are likely if the spine model is oversimplified. In this study, discrepancies in load response introduced by material models will be investigated. Methods Three fiber-reinforced C2-C3 disc models were developed with linear elastic, hyperelastic, and biphasic behaviors. Three different loading modes were investigated: compression, flexion and extension in quasi-static and dynamic conditions. The deformed disc height, disc fluid pressure, range of motion, and stresses were compared. Results Results indicated that the intervertebral disc material model has a strong effect on load-sharing and disc height change when compression and flexion were applied. The predicted mechanical response of three models under extension had less discrepancy than its counterparts under flexion and compression. The fluid-solid interaction showed more relevance in dynamic than quasi-static loading conditions. The fiber-reinforced linear elastic and hyperelastic material models underestimated the load-sharing of the intervertebral disc annular collagen fibers. Conclusion This study confirmed the central role of the disc fluid pressure in spinal load-sharing and highlighted loading conditions where linear elastic and hyperelastic models predicted energy distribution different than that of the biphasic model.

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Section: Discussionsupporting

confidence: 78%

The importance of intervertebral disc material model on the prediction of mechanical function of the cervical spine

Komeili

Rasoulian

Moghaddam

et al. 2021

BMC Musculoskelet Disord

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“…Numerous efforts have been made in developing detailed biomechanical models of the spine based on rigid-body modelling (e.g., Abouhossein et al, 2011;Bruno et al, 2015;Han et al, 2012) or finite element method (e.g., Azari et al, 2018;Ghezelbash et al, 2016). In finite element studies, the complex structures of discs, ligaments and facet joints can be explicitly modelled in detail (Dehghan-Hamani et al, 2019;Khoddam-Khorasani et al, 2018), thereby enabling accurate kinetics analysis in various conditions. Nonetheless, the computational burden is significant (Ghezelbash et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Implementation of physiological functional spinal units in a rigid-body model of the thoracolumbar spine

Wang

Groote

et al. 2020

Journal of Biomechanics

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Most of the current rigid-body models of the complete thoracolumbar spine do not properly model the intervertebral joint as the highly nonlinear stiffness is not incorporated comprehensively and the effects of compressive load on stiffness is commonly being neglected. Based on published in vitro data of individual intervertebral joint flexibility, multi-level six degree-of-freedom nonlinear stiffness of functional spinal units was modelled and incorporated in a rigid-body model of the thoracolumbar spine. To estimate physiological in vivo conditions of the entire spine, stiffening effects caused by directly applied compressive loads, and contributions to mono-segmental stiffness from the rib cage as well as multi-segmental interactions in the thoracic spine were analysed and implemented. Forward dynamic simulations were performed to simulate in vitro tests that measured the load-displacement response of the spine under various loading conditions. The predicted kinematic responses of the model were in agreement with in vitro measurements, with correlations between simulated and measured segmental displacements varying between 0.66 and 0.97 (p < 0.05) and average deviations below 1:6°. Coupling relationships were found between lateral bending and axial rotation. Under compressive loads, the model behaved stiffer and showed a decreased range of motion: The flexion/extension response of the full thoracolumbar spine under compressive loads up to 800 N was found to strongly correlate with the literature (r = 0.99, p < 0.0001). The implementation of physiological functional spinal units with nonlinear stiffness properties into rigid-body models can enhance accuracy of biomechanical simulations, and enable detailed analysis of spinal kinematics under complex loading conditions seen in vivo.

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“…In order to evaluate the outcome of the artificial disc, more biomechanical and patient specific data have to be gathered pre-and postimplantation. Some preliminary work in this direction has already been published [50].…”

Section: Discussionmentioning

confidence: 99%

Compliant Mechanism as a Motion-Preserving Artificial Spinal Disc: A Novel Concept

David

Shoham

2020

Journal of Engineering and Science in Medical Diagnostics and Therapy

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Investigations of spinal disc replacement options have been conducted for several decades but, as yet, the suggested solutions have not been proven to correctly preserve the natural joint motion. This paper focuses on a new structure of an artificial intervertebral disc joint that closely supports a close-to-natural three-dimensional motion of two adjacent vertebrae. The disc design is based on a passive parallel mechanism, with different stiffnesses for each link. Optimization of the artificial disc dimensions and link stiffnesses enabled convergence of the finite screw axis (FSA) of the artificial disc joint with that of a natural disc. As a result, the natural motion of the spine vertebrae was maintained and the loads on the facet joints minimized. The mechanism design was optimized, built, tested, and proven to be a feasible artificial disc with natural motion preservation characteristics.

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Subject‐specific loads on the lumbar spine in detailed finite element models scaled geometrically and kinematic‐driven by radiography images

Cited by 17 publications

References 47 publications

The importance of intervertebral disc material model on the prediction of mechanical function of the cervical spine

The importance of intervertebral disc material model on the prediction of mechanical function of the cervical spine

Implementation of physiological functional spinal units in a rigid-body model of the thoracolumbar spine

Compliant Mechanism as a Motion-Preserving Artificial Spinal Disc: A Novel Concept

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