Subgroup analysis of PD tremor with loading: Action tremor as a combination of classical rest and physiological tremor

Rahimi, Fariborz; Bee, Carina; Wang, David; Janabi–Sharifi, Farrokh; Almeida, Quincy J.

doi:10.1016/j.clinbiomech.2014.12.012

Cited by 1 publication

(1 citation statement)

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“…Therefore, early diagnosis and early treatment of PD patients is essential. 24 Break et al 25 proposed six stages of PD. In stages 3 and 4, substantia nigra, deep midbrain nuclei, and anterior cerebral lobes are involved, resulting in the motor symptoms of PD.…”

Section: Discussionmentioning

confidence: 99%

Correlation between head tremble and the severity of Parkinson’s disease

et al. 2021

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Introduction: Parkinson's (PD) is a common degenerative disease of the central nervous system. It affects more than 6 million individuals worldwide. The typical clinical manifestations include static tremor, slow movement, and unstable posture. However, the correlation between head tremor and the severity of PD remains unclear. Methods:In the current study, 18 patients and 18 healthy subjects were recruited to undergo a phonation test. Noldus facereader 7.0 software was used to analyze the range of head trembling between the two groups. Results:The data revealed that patients with PD had significant differences in the x-, y-, and z-axis of head movement with respect to the specific pronunciation syllables compared with the normal group. Moreover, the head movement of the patients with PD was positively correlated with the severity of the disease in the single, double, and multiple syllable tests. In the phonetic test, the head displacement of patients with PD was significantly greater than that of healthy individuals, and the displacement range was positively correlated with the severity of the disease. Conclusion:These pieces of evidence suggested that the measurement of head displacement assists the early diagnosis and severity of the disease.

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Section: Discussionmentioning

confidence: 99%