Subfoveal choroidal thickness in typical age-related macular degeneration and polypoidal choroidal vasculopathy

Abstract

The choroid under the fovea was thicker in eyes with PCV than those with typical AMD. This result suggests that the choroidal vascular lesion seen in PCV may not be just the choroidal neovascularization accompanied by saccular capillary dilations at the border, but may have a significant structural difference in the choroid compared to typical AMD.

Choroidal changes observed with enhanced depth imaging optical coherence tomography in patients with mild Graves orbitopathy

“…Changes in the choroidal circulation may be related to the pathogenesis of retina, retina pigment epithelium, choroid, and optic nerve. These disorders include hyperopia, 1 myopia, 2 central serous chorioretinopathy, 3 polypoidal choroidal vasculopathy, 4 age-related macular degeneration, 5 inflammatory eye diseases, 6 diabetes, 7 glaucoma, 8 and scleral buckling surgery. 9 The enhanced depth imagingoptical coherence tomography (EDI-OCT) method of spectral domain optical coherence tomography (SD OCT) has enabled the quantitive measurement of choroidal thickness or volume, in addition to obtaining crosssectional images of choroid.…”

Choroidal Thickness and Volume in Healthy Young White Adults and the Relationships between them and Axial Length, Ammetropy and Sex

“…The role of the choroid in a number of diseases, including central serous chorioretinopathy, high myopia, age-related macular degeneration, choroidal melanoma, and polypoidal choroidal vasculopathy, emphasizes the importance of understanding choroidal structure in ocular disease [2][3][4][5] . Indocyanine green has been the best tool for studying choroidal vasculature; however, it does not provide a quantitative evaluation of the layer; other imaging methods such as echography aid in evaluating the layer, and MRI could provide limited imaging of it.…”

“…Although young adult choroidal thickness has been described in previous work using SS-OCT, these studies only focused on thickness at the horizontal and vertical levels that cut the fovea because automated choroidal segmentation software was unavailable and measurement could only take place manually. Measurements of a small number of points can be influenced by local changes in choroidal thickness or irregularities in the choroidoscleral border 5,14,15 .…”

“…Spectral domain OCT (SD-OCT) offers improved axial resolution (3 µm); by providing 19,000 A-scans per second, it shortens examination times, reducing the eye exposure as well as artifacts 1 . The latest development in OCT technology, sweptsource longer-wavelength OCT (SS-OCT), has a longer-band light source than does the conventional instrumentation (1 µm band light source), providing higher penetration through the retinal pigment epithelium (RPE) and allowing for better visualization of the choroid; however, at the present time, SS-OCT use is limited to research.The role of the choroid in a number of diseases, including central serous chorioretinopathy, high myopia, age-related macular degeneration, choroidal melanoma, and polypoidal choroidal vasculopathy, emphasizes the importance of understanding choroidal structure in ocular disease [2][3][4][5] . Indocyanine green has been the best tool for studying choroidal vasculature; however, it does not provide a quantitative evaluation of the layer; other imaging methods such as echography aid in evaluating the layer, and MRI could provide limited imaging of it.…”

Influence of image compression on the interpretation of spectral-domain optical coherence tomography in exudative age-related macular degeneration

“…Choroidal evaluation is important in the diagnosis and post-treatment follow-up of exudative AMD and allied diseases because polypoidal choroidal vasculopathy usually exhibits a thick choroid, 19,20 whereas typical exudative AMD usually exhibits a thin choroid. 19,20 In addition, a recent study suggested that investigating choroidal morphology as well as estimating choroidal thickness are also important in treating exudative AMD. 21 Given this, the uncompressed image may not be substitutable for images with 25% of the quality of JPEG in cases where the quality of the choroidal image is not sufficient.…”