Subcutaneous splenosis: report of a case diagnosed 36 years after splenectomy

Zeebregts, C. J.; Bruyne, C. De; Elbers, Hans R.J.; Morshuis, Wim J.

doi:10.1080/110241598750004823

Cited by 8 publications

(7 citation statements)

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“…The long interval seems to reflect very slow growth of the splenic tissue. Autoimplants of splenic tissue were found in old abdominal surgical scars in eight cases, 1,5 , 7 , 9–12,15 whereas three cases presented at the site of an exit gunshot wound scar 8,14 . The present case was also found in a scar at the site of an exit gunshot wound.…”

Section: Discussionmentioning

confidence: 48%

“…Subcutaneous splenosis is extremely rare. To the best of our knowledge, only 11 cases have been reported in the literature 1,5 , 7–15 . The clinicopathological features of those cases (including the present case) are summarized in Table 2.…”

Section: Discussionmentioning

confidence: 82%

“…In fact, splenosis is now believed to be a fairly common sequel of splenic injury. Peritoneal splenosis has been found in up to 67% of patients with a history of splenic trauma followed by splenectomy 5,15 . In most cases of splenosis, the pathogenesis is believed to be a mechanical implantation of splenic tissue, most commonly on peritoneal or serosal surfaces, following traumatic or surgical injury of the splenic capsule.…”

Section: Discussionmentioning

confidence: 99%

“…Extraperitoneal splenosis is a rare condition, which most commonly occurs in thoracic cavity after thoracoabdominal trauma with simultaneous injuries of spleen and diaphragm 1,4 , 5 . Other extraperitoneal locations that have been reported include liver, 1 kidney, 2,3 pericardial sac, 6 subcutaneous tissue, 1,5 , 7–15 and cerebrum 16 . Extraperitoneal splenosis presumably occurs when splenic fragments escape the peritoneal cavity through a path created by traumatic injury.…”

Section: Discussionmentioning

confidence: 99%

“…Subcutaneous splenosis is an extremely rare condition mostly observed in abdominal wall surgical scars. Because only 11 cases of subcutaneous splenosis have been reported to date, 1,5 , 7–15 we would like to report another case of subcutaneous splenosis identified histopathologically and confirmed by immunohistochemical study.…”

mentioning

confidence: 97%

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Unusual subcutaneous splenosis occurring in a gunshot wound scar: Pathology and immunohistochemical identification

Yeh

Chuang

Kuo

2006

Pathology International

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Splenosis usually occurs after traumatic rupture of the spleen with autotransplantation of splenic tissue to ectopic sites. Most commonly, it occurs as intraperitoneal nodules, which are found either incidentally or after symptomatic complications. Subcutaneous splenosis is a rare condition mostly observed in abdominal surgical scars. Reported herein is a case of subcutaneous splenosis developed in an exit gunshot wound scar on the left lower chest wall 9 years after splenectomy. The lesion presented as an asymptomatic subcutaneous nodule, which was excised under the impression of a skin tumor. Microscopically, there were multiple subcutaneous nodules resembling splenic tissue with red and white pulp. They were confirmed to be ectopic splenic tissue by immunohistochemical staining of the vascular lining cells (CD8+, CD31+, and CD34-). Only 11 cases of subcutaneous splenosis have been reported before. The present case was the third case occurring in an exit gunshot wound scar, and the diagnosis was confirmed by immunohistochemical study.

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Section: Discussionmentioning

confidence: 48%

Section: Discussionmentioning

confidence: 82%

Section: Discussionmentioning

confidence: 99%