Sarcoidosis is a disease which still has uncertain etiology. Possible
environmental causes are cited in the literature, like organic and inorganic
particles and infectious agents. Recent studies have demonstrated the occurrence
of sarcoidosis in patients with chronic C hepatitis; however, this association
remains without statistical or causal evidence. In this report a case of
sarcoidosis associated with chronic hepatitis C will be described, with
subcutaneous lesions, considered rare, and good response to treatment with
colchicine and prednisone. The hepatitis C virus was isolated in sarcoid tissue
and the association between the two diseases will be discussed.